Low Concentration Atropine for Myopia Progression in School Children
- Registration Number
- NCT02130167
- Lead Sponsor
- Chang Gung Memorial Hospital
- Brief Summary
Myopia is the leading cause of blindness in Taiwan. The younger children with myopia, the higher risk of high myopia in later life and complications such as retinal detachment and maculopathy will occur. We have reported the low concentration of atropine (0.05%) with the effect on retarding the myopia progression. Recently the 0.01% atropine was also reported effective and with less visual side effects such as mydriasis. The aim of this study is to compare the efficacy in controlling myopia progression and visual side effects of 2 low concentration of atropine(0.05% vs 0.01%) in children aged 6-12 years with myopia of at least -0.5 diopters (D) and astigmatism of -1.50 D or less.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Myopia of at least -0.5 diopters (D) and astigmatism of -1.50 D or less.
strabismus, amblyopia. cataract, glaucoma or any ocular diseases ocular surgery history systemic diseases (ex. asthma, heart disease...)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 0.05% Atropine Atropine - 0.01% Atropine Atropine -
- Primary Outcome Measures
Name Time Method Cycloplegic spherical refraction change 1 year Cycloplegic spherical refraction change is the main indicator of the myopia progression.
- Secondary Outcome Measures
Name Time Method Axial length change 1 year Axial length change is another indicator of the myopia progression.Using non-contact biometry. unit: millimeter(mm)
Trial Locations
- Locations (1)
Kaohsiung Chang Gung Memorial Hospital
🇨🇳Kaohsiung, Taiwan