A Clinical Trial to study the Combined Effect of Mahatriphla Ghrita with Ayurvedic Therapy patients with Adhimantha (primary open angle glaucoma)

Phase 1/2

Recruiting

• Conditions: Open-angle glaucoma. Ayurveda Condition: ADHIMANTHAH,

• Registration Number: CTRI/2022/05/042635
• Lead Sponsor: Patanjali Bhartiya Ayurvigyan evam Anusandhana Sansthana Haridwar

Brief Summary

This study is a randomized, open-labeled, parallel-group, clinical trial, to the evaluation of the combined effect of Mahatriphladi ghrita Nasya, Tarpana, pana and Rakta-mokshana in Adhimantha (POAG). patients of Adhimantha (POAG) will be selected from the OPD/IPD of shalakya department of Patanjali ayurvedic hospital, Haridwar, Uttarakhand and shri krishna eye institute Haridwar. The study will be conducted on a total of 30 patients (15 patients in each group) based on inclusion and exclusion criteria depending on the detailed clinical history, physical examination, and other necessary investigation and irrespective of their gender, caste, or creed.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-23
• Last Update Posted: 2022-07-22

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Age 30 To 70 years 2.
• Patients of either sex.
• Patients of POAG having IOP < 21mmHg and IOP > 21 mmHg. 4.
• Visual acuity more than 6/60 and clear media.
• Patients of POAG.

Exclusion Criteria

• 1.Age below 30 years and above 70 years.
• Visual acuity less than 6/60 3.
• Secondary and developmental Glaucoma including exfoliative glaucoma, pigmentary glaucoma,trauma-induced, inflammatory glaucoma, family history of glaucoma 4.
• Evidence of any anterior segment pathology like conjunctivitis, keratitis, or acute uveitis.
• History of opaque ocular media (as in cataracts, corneal opacities, vitreous opacities).
• Pregnant women 7.Any malignancy, uncontrolled diabetes, uncontrolled hypertension.
• Contraindicated for Nasya.
• 10.Contraindicated for Tarpana.
• Contraindicated for Rakta-mokshana (jalaukavcharan).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
SUBJECTIVE PARAMETER	for subjective parameter 1st and 90th day
1.Blurred vision	for subjective parameter 1st and 90th day
2.Frequent change of presbyopic glasses	for subjective parameter 1st and 90th day
5.Headache	for subjective parameter 1st and 90th day
3.Delayed dark adaptation	for subjective parameter 1st and 90th day
4.Visual field defect	for subjective parameter 1st and 90th day

Secondary Outcome Measures

Name	Time	Method
OBJECTIVE PARAMETERS: -	1.Visual Acuity using Snellen’s chart

Trial Locations

Locations (1)

Patanjali bhartiya ayurvigyan evam anusandhana Sansthana haridwar; 🇮🇳 Hardwar, UTTARANCHAL, India

Patanjali bhartiya ayurvigyan evam anusandhana Sansthana haridwar

🇮🇳Hardwar, UTTARANCHAL, India

ARCHANA BARTWAL

Principal investigator

9818747297

drarchanabartwal91@gmail.com