NCT06565351已完成不适用
Feasibility of Replacing 99mTc-DTPA GFR Measurements With eGFR From s-Cystatin C in Individuals With Spinal Cord Injuries
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 248
- 试验地点
- 1
- 主要终点
- Estimated clearance of Cystatin C (eGFR cystatin C)
研究概览
简要总结
- In individuals with spinal cord injury (SCI) kidney function defined as Glomerular Filtration Rate (GFR) is monitored by injection of e.g.99mDTPA and subsequent blood sampling (DTPA-clearance)
- GFR calculated from plasma samples of the endogenous substance s-Cystatin C (eGFR cystatin C) was compared to DTPA-clearance in 248 individuals with SCI.
- It is concluded that eGFR based on plasma s-cystatin C can replace the more tedious 99mDTPA-clearance procedures in individuals with SCI
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Neurogenic bladder dysfunction due to spinal cord injury
排除标准
- 未提供
结局指标
主要结局
Estimated clearance of Cystatin C (eGFR cystatin C)
时间窗: through study period (2 years)
The estimated clearance of cystatin (eGFR) C is calculated from s-cystatin C and the age and height and weight of the individual. It is corrected for Body Surface area. In this study it is compared to the Gold Standard examination DTPA-clearance
次要结局
- Test/ retest variability of eGFR cystatin C(Up to three months)
- Long term repeatability of eGFR cystatin C(Up to three years)
研究者
Ulrik Bjoern Andersen
Senior Consultant
Rigshospitalet, Denmark
研究点 (1)
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