Comparison of Anti Pneumococcal Vaccinal Response in HIV-positive Adults

Phase 1

• Conditions: HIV infected patients; B04.820.650.589.650.350; D20.215.894.135.750.600

• Registration Number: RBR-3p7577
• Lead Sponsor: Hospital das Clínicas da Faculdade de Medicina da USP

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-03-13
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: data analysis completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

All individuals aged 18-60 years with HIV infection documented by enzyme-linked immunosorbent assay (ELISA) and Western-Blot testing, and with T-CD4 count above 200 cells/mm3 in two different occasions in the past six months were eligible. Were included in trial individuals who demonstrated understanding and signed consent form.

Exclusion Criteria

Exclusion criteria included: any acute febrile illness at the moment of vaccination, active AIDS-defining clinical condition, previous immunization with any of the pneumococcal vaccines, any systemic malignancy neoplasm, use of immunoglobulin within the last three months, current pregnancy, antecedent of allergy to any of the pneumococcal vaccine components.

Study & Design

• Study Type: Intervention
• Study Design: Not specified