Clinical study on the interrelationship between liver, heart, and lung in portal hypertensio
Not Applicable
Recruiting
- Conditions
- Portal hypertension
- Registration Number
- JPRN-UMIN000042876
- Lead Sponsor
- Chiba University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Patients whom the principal investigator or sub-investigator judges to be inappropriate as subjects. (2) Patients for whom outpatient follow-up at our hospital is difficult.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of cirrhotic cardiomyopathy and portopulmonary hypertension in patients with portal Hypertension and at 3 months and 1 year
- Secondary Outcome Measures
Name Time Method a. Examine the relationship between liver reserve values (blood chemistry, Child-Pugh score, MELD score, and liver elasticity) and cardiac and portopulmonary hypertension factors. b. Examine the relationship between portal hemodynamic severity (hepatic venous pressure gradient, Doppler flow factors in portal vein and portosystemic shunt) and cardiac function factors and pulmonary hypertension factors. c. To examine changes in cardiac function and pulmonary hypertension factors after treatment of complications associated with portal hypertension. d. Examine the relationship of prognosis to cardiac function and pulmonary hypertension factors. e. Examine differences in endothelin, cytokines, and BMP9 by angiographic site and changes after treatment.