Effect of Plantar Vibration Therapy On Sensation and Nerve Conduction Velocity Of Plantar Nerve In Diabetic Neuropathy
Overview
- Phase
- Phase 1
- Status
- Not yet recruiting
- Sponsor
- Kratika Dubey
- Enrollment
- 42
- Locations
- 1
- Primary Endpoint
- Nerve conduction velocity.
Overview
Brief Summary
Diabetes is a very common condition affecting 101 million population of India in 2021 (1). Chronic diabetes leads to several complications.
Diabetic peripheral neuropathy (DPN) is one of the most common complications of patients with Type 2 diabetes mellitus (T2DM), which affects sensation, proprioception and somatosensory information.
The symptoms of diabetic neuropathy include reduced sensation, numbness, burning sensation, and pain, especially in the lower extremities due to nerve damage .Tactile sensations mostly affected in this condition.Chronic neuropathy when not managed leads to further complication like diabetic foot.
Currently, diagnosis of diabetic PN is mostly clinical, further confirmed by nerve conduction study (NCS) of peripheral sensory nerves.Plantar nerve is the major nerve supply of the distal lower limb.
vibration therapy improves reduces the pain intensity, improves the glycemic control, skin blood flow, muscle strength, which makes it applicable for DPN prevention or for delaying its progression.Localised plantar vibration has shown to improve proprioception and balance in diabetic patients
There are studies which indicates that nerve conduction velocity of plantar nerve is a predictor for diabetic foot which can be caused by chronic peripheral neuropathy.
Predicting diabetic foot in pre-symtomatic stage would aid in foot care and prevent further complications.
Vibration therapy has shown effects on blood flow, strength and flexibility. So there was a need to study if the vibration therapy affects nerve conduction velocity of plantar nerve.
Study Design
- Study Type
- Interventional
- Allocation
- Coin toss, Lottery, toss of dice, shuffling cards etc
- Masking
- Participant Blinded
Eligibility Criteria
- Ages
- 35.00 Year(s) to 80.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Cut off of cut-off of Plantar nerve -SNAP amplitude of 4.55 lV and 2.65 lV Type 2 diabetes mellitus of minimum 8 years Diagnosed DPN for more than 1 year, Age between 35 yr and above.
- •More than 2.5 score in Michigan neuropathy screening instrument.
Exclusion Criteria
- •Patient diagnosed with mental disease.
- •Patients having impaired vibration sensation orthopedic, neurological disorders related to balance disturbances,skin lesions.
- •Bone deformities in the feet.
Outcomes
Primary Outcomes
Nerve conduction velocity.
Time Frame: 1) At the biginning of the study | 2) at the end of the study ( after 3 weeks)
Monofilament for sensation
Time Frame: 1) At the biginning of the study | 2) at the end of the study ( after 3 weeks)
Tuning fork and pin for sensation.
Time Frame: 1) At the biginning of the study | 2) at the end of the study ( after 3 weeks)
• Michigan Neuropathy Screening Instrument
Time Frame: 1) At the biginning of the study | 2) at the end of the study ( after 3 weeks)
Secondary Outcomes
No secondary outcomes reported
Investigators
Kratika Dubey
DR. D.Y. Patil College of Physiotherapy