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临床试验/NCT03346512
NCT03346512已完成不适用

Considerations on the Transfusion Threshold in Cardiac Surgery

Pierre Wauthy1 个研究点 分布在 1 个国家目标入组 852 人开始时间: 2016年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
852
试验地点
1
主要终点
Hemoglobin rate

研究概览

简要总结

This is a retrospective observational study of the transfusion threshold in cardiac surgery.

There is controversy in the literature regarding the transfusion threshold to be adopted, especially in a patient who has undergone cardiac surgery. Some authors suggest that the transfusion should be done in a restrictive way when a certain threshold in hemoglobin is reached, in order to avoid the risks it implies, especially infectious.This threshold is very controversial and remains to be defined (variations in the literature from 7g / dL to 9g / dL). Other authors conclude that there is no superiority of a restrictive transfusion compared to a more liberal transfusion, with regard to the morbidity or medical costs.

It is therefore interesting to study, in a retrospective manner, the global and multidisciplinary management of patients who have undergone a cardiac surgery within the CHU Brugmann hospital, to analyze if they have been adequately transfused.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients having undergone cardiac surgery (other than the placement of a pacemaker or defibrillator) within the CHU Brugmann hospital between 2006 and 2015

排除标准

  • 未提供

结局指标

主要结局

Hemoglobin rate

时间窗: Five days after surgery (J5)

Hemoglobin rate

Liquid balance

时间窗: One day after surgery

Ratio between total fluid intake (perfusion) and loss (blood and urine)

Hematocrit rate

时间窗: Five days after surgery (J5)

Hematocrit rate

Creatinin rate

时间窗: Five days after surgery (J5)

Renal function indicator

International Normalized Ratio (INR)

时间窗: Five days after surgery (J5)

Coagulation indicator

Total amount of blood perfusions

时间窗: Five days after surgery (J5)

Total amount of blood perfusions

次要结局

未报告次要终点

研究者

发起方
Pierre Wauthy
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Pierre Wauthy

Head of clinic

Brugmann University Hospital

研究点 (1)

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