Considerations on the Transfusion Threshold in Cardiac Surgery

Completed

• Conditions: Cardiac Surgery
• Interventions: Procedure: Cardiac surgery

• Registration Number: NCT03346512
• Lead Sponsor: Pierre Wauthy

Brief Summary

This is a retrospective observational study of the transfusion threshold in cardiac surgery.

There is controversy in the literature regarding the transfusion threshold to be adopted, especially in a patient who has undergone cardiac surgery. Some authors suggest that the transfusion should be done in a restrictive way when a certain threshold in hemoglobin is reached, in order to avoid the risks it implies, especially infectious.This threshold is very controversial and remains to be defined (variations in the literature from 7g / dL to 9g / dL). Other authors conclude that there is no superiority of a restrictive transfusion compared to a more liberal transfusion, with regard to the morbidity or medical costs.

It is therefore interesting to study, in a retrospective manner, the global and multidisciplinary management of patients who have undergone a cardiac surgery within the CHU Brugmann hospital, to analyze if they have been adequately transfused.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-02
• Primary Completion: 2016-06-14
• Study Completion: 2016-06-14
• Study First Submitted: 2017-11-15
• Study First Submitted QC: 2017-11-15
• Study First Posted: 2017-11-17
• Status Verified: 2019-04
• Last Update Submitted: 2019-04-18
• Last Update Posted: 2019-04-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 852

Inclusion Criteria

• Patients having undergone cardiac surgery (other than the placement of a pacemaker or defibrillator) within the CHU Brugmann hospital between 2006 and 2015

Exclusion Criteria

• N/A

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Cardiac surgery	Cardiac surgery	Patients having undergone cardiac surgery (other than the placement of a pacemaker or defibrillator) within the CHU Brugmann hospital between 2006 and 2015

Primary Outcome Measures

Name	Time	Method
Hemoglobin rate	Five days after surgery (J5)	Hemoglobin rate
Liquid balance	One day after surgery	Ratio between total fluid intake (perfusion) and loss (blood and urine)
Hematocrit rate	Five days after surgery (J5)	Hematocrit rate
Creatinin rate	Five days after surgery (J5)	Renal function indicator
International Normalized Ratio (INR)	Five days after surgery (J5)	Coagulation indicator
Total amount of blood perfusions	Five days after surgery (J5)	Total amount of blood perfusions

Trial Locations

Locations (1)

CHU Brugmann; 🇧🇪 Brussels, Belgium