Hyperthyroidism: Methimazole Plus L-carnitine and Selenium
Not Applicable
- Conditions
- Hyperthyroidism
- Interventions
- Dietary Supplement: L-carnitine+Selenium
- Registration Number
- NCT04946123
- Lead Sponsor
- Lo.Li.Pharma s.r.l
- Brief Summary
The study aims to investigate the benefits of methimazole treatment in patients with hyperthyroidism, associated with supplementation of L-carnitine and Selenium.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Diagnosis of hyperthyroidism requiring therapy with methimazole
Exclusion Criteria
- Drug and alcohol abuse;
- Pregnancy;
- Medically uncontrolled psychiatric conditions;
- Interfering therapies (lithium, interferone, TKI, amiodarone)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description methimazole+L-carnitine+selenium (intervention) L-carnitine+Selenium Patients with hyperthyroidism under methimazole treatment + supplementation with L-carnitine and Selenium
- Primary Outcome Measures
Name Time Method Hyperthyroidism symptoms Change from 6-months supplementation QoL at 12 months of intervention (end of study) Improvement of the patients' quality of life through questionnaire
- Secondary Outcome Measures
Name Time Method TRAb Four time points: baseline; after 3 months of supplementation; after 6 months of supplementation; end of the study (12 months) Change in serum TRAb (TSH receptor antibodies)
TSH Four time points: baseline; after 3 months of supplementation; after 6 months of supplementation; end of the study (12 months) Change in serum TSH (Thyroid stimulating hormone)
Trial Locations
- Locations (1)
Azienda Ospedaliero-Universitaria Città della scienza e degli studi di Torino
🇮🇹Torino, Italy