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Clinical Trials/ISRCTN03884521
ISRCTN03884521
Completed
Not Applicable

Enhancing the effect of physical therapy for motor impairment after stroke with Theta Burst Stimulation

niversity College London Hospitals NHS Foundation Trust (UK)0 sites45 target enrollmentApril 29, 2010
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ConditionsTopic: Stroke Research NetworkSubtopic: RehabilitationDisease: Therapy typeCirculatory SystemStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Topic: Stroke Research Network
Sponsor
niversity College London Hospitals NHS Foundation Trust (UK)
Enrollment
45
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 29, 2010
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity College London Hospitals NHS Foundation Trust (UK)

Eligibility Criteria

Inclusion Criteria

  • •1\. History of a single ischaemic stroke, initially affecting the hand
  • •2\. Minimum interval since stroke onset one year (no upper limit)
  • •3\. Residual impairments of hand function (strength and/or dexterity)
  • •4\. Some degree of hand movement defined as present wrist extension (\>\=20%) and ability to grasp
  • •5\. Capable of giving informed consent
  • •6\. Aged 18 \- 80 years, either sex

Exclusion Criteria

  • •1\. Intracerebral hemorrhage
  • •2\. Large ischaemic lesions involving almost the whole MCA territory
  • •3\. Significant tone problems in the hand (greater than 2 in the Ashworth Scale)
  • •4\. Severe cognitive impairment defined as mini\-mental state examination (MMSE) less than 20
  • •5\. Residual aphasia or visual field defect (greater than or equal to 2 in the relative item of the National Institutes of Health Stroke Scale \[NIHSS])
  • •6\. Past or current history of other neurological or psychiatric disease including epilepsy, previous or recurrent stroke and peripheral neuropathy
  • •7\. Major systemic illness
  • •8\. Use of anticonvulsant, psychotropic or sedative or medication
  • •9\. Excessive use of alcohol or other substances
  • •10\. Accepted contraindications for TMS (presence of metal in the head (excluding the mouth), intracardiac lines, cardiac pacemakers)

Outcomes

Primary Outcomes

Not specified

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