Enhancing the effect of physical therapy for motor impairment after stroke with Theta Burst Stimulation

niversity College London Hospitals NHS Foundation Trust (UK)0 个研究点目标入组 45 人开始时间: 2010年4月29日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. History of a single ischaemic stroke, initially affecting the hand
•2. Minimum interval since stroke onset one year (no upper limit)
•3. Residual impairments of hand function (strength and/or dexterity)
•4. Some degree of hand movement defined as present wrist extension (>=20%) and ability to grasp
•5. Capable of giving informed consent
•6. Aged 18 - 80 years, either sex

•1. Intracerebral hemorrhage
•2. Large ischaemic lesions involving almost the whole MCA territory
•3. Significant tone problems in the hand (greater than 2 in the Ashworth Scale)
•4. Severe cognitive impairment defined as mini-mental state examination (MMSE) less than 20
•5. Residual aphasia or visual field defect (greater than or equal to 2 in the relative item of the National Institutes of Health Stroke Scale [NIHSS])
•6. Past or current history of other neurological or psychiatric disease including epilepsy, previous or recurrent stroke and peripheral neuropathy
•7. Major systemic illness
•8. Use of anticonvulsant, psychotropic or sedative or medication
•9. Excessive use of alcohol or other substances
•10. Accepted contraindications for TMS (presence of metal in the head (excluding the mouth), intracardiac lines, cardiac pacemakers)

发起方

niversity College London Hospitals NHS Foundation Trust (UK)