Bach flower remedies and homoeopathic medicines for treatment of depressio

Phase 4

• Conditions: Health Condition 1: F330- Major depressive disorder, recurrent, mild

• Registration Number: CTRI/2022/12/047973
• Lead Sponsor: D N De Homoeopathic Medical College and Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 January 2023

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1. Cases suffering from depression, diagnosed as per DSM-V criteria [13]

2. Mild (HDRS <= 13) to moderate (HDRS 14-18) cases of depression.

3. Patients must not have been taking antidepressants or anxiolytic drugs at

the time of inclusion.

4. Patients of either sex

5. Age between 18 and 65 years

6. Capability and willingness to give informed consent and to comply with the study procedures

7. Literate patients who can read English, Bengali/or Hindi.

Exclusion Criteria

1. Severe or very severe depression (HDRS > 19); ± suicide attempt

2. Spontaneous improvement by >= 25% in HDRS during the 1-week placebo run-in prior trial enrolment

3. Patients with other psychiatric diseases; e.g., schizophrenia or other psychotic disorders, bipolar affective disorder, schizoaffective disorders, alcohol or other substance abuse, eating disorders, psychosis, mania, hypomania or any other Axis I disorder except panic disorder, personality disorders, history of seizures

4. A clinically significant acute or chronic disease that would hinder regular participation in the study

5. Treatment with antipsychotics, antidepressants, sedatives/hypnotics or mood stabilizers four weeks prior to the screening

6. Complementary or alternative treatment used simultaneously to the study (e.g., acupuncture, phytotherapy, psychotherapy etc.)

7. Homeopathic treatment for any chronic diseases eight weeks prior to study entry

8. Cases suffering from uncontrolled systemic illness or life-threatening infections

9. Self-reported immune-compromised state

10. Pregnant and puerperal women, lactating mothers

11. Substance abuse and/or dependence

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hamilton Depression Rating ScaleTimepoint: Baseline and every month, up to 3 months.

Secondary Outcome Measures

Name	Time	Method
Becks Depression InventoryTimepoint: Baseline and every month, up to 3 months.