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The effectiveness of Vitamin E in the treatment of wounds found in the mouth of patients admitted to the intensive care unit of a reference hospital in the state of Ceará

Phase 2
Conditions
Other and unspecified lesions of oral mucosa
S01.5
Registration Number
RBR-6mb4b77
Lead Sponsor
Hospital de Messejana Dr. Carlos Alberto Studart Gomes
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruitment completed
Sex
Not specified
Target Recruitment
Not specified
Inclusion Criteria

Individuals (American Society of Anesthesiologists) ASA II and III of both sexes; age between 30 and 65 years; having lesions in the oral cavity; admitted to intensive care units; and with injuries acquired during the hospitalization period

Exclusion Criteria

Volunteers with a confirmed history of allergy to tocopherol (Vit. E); pregnant or breastfeeding women; patients whose injury has its origins in the community, prior to hospitalization

Study & Design

Study Type
Intervention
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Evaluation of scar repair. The measurement of the outcome related to the scar repair of the injury will be carried out using a caliper, in which, in the initial consultations, 24h, 72h, 7 days and 14 days, two measurements will be taken: buccolingual (d) and mesiodistal (D ) of the injury, in order to observe the healing process. Such measurements will be made in triplicate, then obtaining an arithmetic average to which the following formula will be applied, in order to obtain the area: (A= p. d. D/4). To measure the contraction of the lesion, the initial area will be subtracted from the other areas (24h, 72h, 7 days and 14 days).
Secondary Outcome Measures
NameTimeMethod
o secondary stages expected
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