SUTURE-CLOSURE OMENTOPEXY VERSUS OMENTOPEXY ALONE IN REPAIR OF PERFORATED PEPTIC ULCER
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Early postoperative follow up for repair of perforated peptic ulcer
研究概览
简要总结
The present study will be conducted to assess whether there is a direct benefit associated with modified-Graham's omentopexy (MGO), above and beyond the benefit associated with Graham's omentopexy (GO) in the treatment of perforated duodenal ulcers. We attempted to answer the question whether primary closure of the perforation in MGO will affect the outcome of surgery. Complication rates will be compared for the two alternative surgical procedures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- All adult patients of both sexes with a clinical diagnosis of perforated peptic ulcer (gastric or duodenal) that are fit to undergo surgery.
排除标准
- •Patients with associated bleeding ulcer (additional steps are needed to control bleeding).
- •2. Patients with associated pathology other than perforated peptic ulcer that needs surgical intervention.
研究组 & 干预措施
SUTURE-CLOSURE OMENTOPEXY IN REPAIR OF PERFORATED PEPTIC ULCER
Group (A ) includes modification of the Graham's patch will be used in this group, where suitable sutures are passed between the edges of perforation and tied to close the perforation. A pedicle of omentum based on right omental artery is brought between these sutures, and these sutures are tied again with pedicle of omentum between knots over the perforation (thus the omentum remains sandwiched between the two levels of secured knots).
干预措施: SUTURE-CLOSURE OMENTOPEXY IN REPAIR OF PERFORATED PEPTIC ULCER (Procedure)
OMENTOPEXY ALONE IN REPAIR OF PERFORATED PEPTIC ULCER
Group (B) includes Grahm's technique of omentopexy will be performed by closing the perforation by placing interrupted full thickness suitable sutures along the margins of the ulcer with a patch of pedicled omentum laid over these sutures, which are then tied (without any attempt for primary closure of the perforation before placing the omentum as a plug).
干预措施: OMENTOPEXY ALONE IN REPAIR OF PERFORATED PEPTIC ULCER (Procedure)
结局指标
主要结局
Early postoperative follow up for repair of perforated peptic ulcer
时间窗: Three days after the operation
resumption of oral intake
次要结局
未报告次要终点
研究者
Adel Ashraf Abdrabou
Resident in the Department of General Surgery, oncological and Laparoscopic Surgery Sohag University Hospital
Sohag University