SUTURE-CLOSURE OMENTOPEXY VERSUS OMENTOPEXY ALONE IN REPAIR OF PERFORATED PEPTIC ULCER

Not Applicable

Recruiting

• Conditions: Perforated Peptic Ulcer
• Interventions: Procedure: SUTURE-CLOSURE OMENTOPEXY IN REPAIR OF PERFORATED PEPTIC ULCER; Procedure: OMENTOPEXY ALONE IN REPAIR OF PERFORATED PEPTIC ULCER

• Registration Number: NCT06550856
• Lead Sponsor: Sohag University

Brief Summary

The present study will be conducted to assess whether there is a direct benefit associated with modified-Graham's omentopexy (MGO), above and beyond the benefit associated with Graham's omentopexy (GO) in the treatment of perforated duodenal ulcers. We attempted to answer the question whether primary closure of the perforation in MGO will affect the outcome of surgery. Complication rates will be compared for the two alternative surgical procedures.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-07-15
• Status Verified: 2024-08
• Study First Submitted: 2024-08-08
• Study First Submitted QC: 2024-08-08
• Last Update Submitted: 2024-08-08
• Study First Posted: 2024-08-13
• Last Update Posted: 2024-08-13
• Primary Completion: 2025-05-01
• Study Completion: 2025-05-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• All adult patients of both sexes with a clinical diagnosis of perforated peptic ulcer (gastric or duodenal) that are fit to undergo surgery.

Exclusion Criteria

• 1. Patients with associated bleeding ulcer (additional steps are needed to control bleeding).

2. Patients with associated pathology other than perforated peptic ulcer that needs surgical intervention.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
SUTURE-CLOSURE OMENTOPEXY IN REPAIR OF PERFORATED PEPTIC ULCER	SUTURE-CLOSURE OMENTOPEXY IN REPAIR OF PERFORATED PEPTIC ULCER	Group (A ) includes modification of the Graham's patch will be used in this group, where suitable sutures are passed between the edges of perforation and tied to close the perforation. A pedicle of omentum based on right omental artery is brought between these sutures, and these sutures are tied again with pedicle of omentum between knots over the perforation (thus the omentum remains sandwiched between the two levels of secured knots).
OMENTOPEXY ALONE IN REPAIR OF PERFORATED PEPTIC ULCER	OMENTOPEXY ALONE IN REPAIR OF PERFORATED PEPTIC ULCER	Group (B) includes Grahm's technique of omentopexy will be performed by closing the perforation by placing interrupted full thickness suitable sutures along the margins of the ulcer with a patch of pedicled omentum laid over these sutures, which are then tied (without any attempt for primary closure of the perforation before placing the omentum as a plug).

Primary Outcome Measures

Name	Time	Method
Early postoperative follow up for repair of perforated peptic ulcer	Three days after the operation	resumption of oral intake

Trial Locations

Locations (1)

Sohag university Hospital; 🇪🇬 Sohag, Egypt