Study to find Effects of Chandraprabha Vati(Ayurvedic Medicine) in Polycystic Ovarian Syndrome Characterised by Small cysts in ovary with irregular,Scanty menses and excess/unwanted hairs on Face,Thighs,Abdomen etc.

Phase 2

Conditions: Health Condition 1: E282- Polycystic ovarian syndrome

Registration Number: CTRI/2020/11/028824

Lead Sponsor: iranjan Ashok Dumbare

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1.Patients of age group 19-35 years.

2.Diagnosed cases of PCOS (Rotterdam Criteria) Any 2/3

a)Hyperandrogenism (Clinical or Biochemical)

b)Oligomenorrhea (Menstrual cycle > 35days)/ Secondary Amenorrhea (Menstrual cycle > 90 days but <180 days)

c) USG findingsâ?? PCO features on USG i.e. Peripherally arranged Antral Follicle Count >12 with thickened stroma in Ovaries And OR Ovarian Volume >10 cm3 in Unilateral or Bilateral ovaries.

3.Both Unmarried and Married patients of PCOS.

Exclusion Criteria

1.Patients of age group < 19 yrs and > 35 yrs.

2.Patients showing signs and symptoms other than PCOS.

3.Patients having any other disease causing Oligomenorrhea & Anovulation excluding PCOS on above criteria i.e.Hypogonadotrophic Hypogonadism, Premature Ovarian Failure.

4.Patients suffering from a) Congenital Adrenal Hyperplasia b) Severe Insulin resistance(Insulin dependant Diabetes Mellitus) c)Androgen secreting Ovarian & Adrenal tumors d)Thyroid abnormalities e) Cushingâ??s syndrome f)Cardiac disease g) Hyperprolactenemia

5.Patients with any organic lesions of Reproductive Tract like TB, Ca, Congenital anomalies, any other pelvic pathologies.

6.A current or previous (within 3 months) use of OC Pills, Glucocorticoids, Antiandrogens, Antidiabetics, Antiobesity drugs or any Hormonal Therapy.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Menstrual History For Interval between 2 cycles. 2.modified Ferriman Gallwey Score for HirsutismTimepoint: At Enrollment and After 6 months

Secondary Outcome Measures

Name	Time	Method
BMI IN KG/M2 <br/ ><br>Sr.Testesterone Sr.Insulin (F) BSL(F) <br/ ><br>USG (Pelvis)TAS OR TVS <br/ ><br>1)PCOS Pattern 2)Ovarian volume <br/ ><br>Timepoint: At Enrollment and After 6 months