A Clinical trial to study the effects of two techniques-using patients own blood and fibrin glue-for conjunctival graft adherence in pterygium surgery
- Conditions
- Pterygium of eye,
- Registration Number
- CTRI/2013/06/003764
- Lead Sponsor
- Dr Abraham Kurian
- Brief Summary
This study is a randomised controlled,parallel group interventional single centre trial to compare the efficacy and outcome of Autologous blood and fibrin glue for conjunctival graft adherence in sutureless pterygium surgery, in 200 patients with primary pterygia. The patients are randomly assigned to two groups-Group I - using autologous blood and Group II - using fibrin glue.The primary outcome measures will be the graft adherence assessed at 1 day and 1 week and recurrence at 1 year postoperatively. Secondary outcome measures will be incidence of graft related complications at 1 day, 1 week and 1 month postoperatively.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 200
Clinically significant primary pterygia.
1)Recurrent Pterygium 2)Patients with significant ocular surface disease 3)Patients with known hypersensitivity to fibrin glue or any of its components 4)Patients on Anticoagulants or antirheological agents (as these are thought to have an adverse effect on the adherence of the graft with autologous blood).
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 2)Recurrence 1)1 day,1 week | 2)1 year 1)Graft adherence 1)1 day,1 week | 2)1 year
- Secondary Outcome Measures
Name Time Method Complications like Graft retraction,Subconjunctival haemorrhage 1 day,1 week,1month
Trial Locations
- Locations (1)
Chaithanya Eye Hospital and Research Institute
🇮🇳Thiruvananthapuram, KERALA, India
Chaithanya Eye Hospital and Research Institute🇮🇳Thiruvananthapuram, KERALA, IndiaDr Abraham KurianPrincipal investigator919847094478abrahamkurian55@yahoo.in