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Clinical Trials/NCT06444230
NCT06444230
Completed
N/A

Effects Of Routine Physical Therapy With And Without Neuro-Developmental Technique On Gross Motor Function, Spasticity And Health Related Quality Of Life In Diplegic Cerebral Palsy- A Randomized Controlled Trail

University of Lahore1 site in 1 country72 target enrollmentJuly 27, 2023
ConditionsCerebral Palsy

Overview

Phase
N/A
Intervention
Not specified
Conditions
Cerebral Palsy
Sponsor
University of Lahore
Enrollment
72
Locations
1
Primary Endpoint
Modified Ashworth Scale
Status
Completed
Last Updated
last year

Overview

Brief Summary

The aim of this study is to investigate the effects of routine physical therapy with and without neurodevelopmental technique on gross motor function, spasticity and health related quality of life in diplegic cerebral palsy.

Detailed Description

The neurological illness known as cerebral palsy is caused by damage to the growing brain and therefore is indicated by anomalies of muscle strength, mobility, and motor functions. Cerebral palsy affects posture, muscle tone, and movement development. Neurodevelopmental technique and routine physical therapy are considered to be effective in treatment of cerebral palsy. This study will investigate the combined effects of neurodevelopmental technique and routine physical therapy versus routine physical therapy on gross motor function, spasticity, and health related quality of life in diplegic cerebral palsy.

Registry
clinicaltrials.gov
Start Date
July 27, 2023
End Date
April 1, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University of Lahore
Responsible Party
Principal Investigator
Principal Investigator

Shehzeena Ashraf

Principal Investigator

University of Lahore

Eligibility Criteria

Inclusion Criteria

  • Patients with an age of 8 to 18 years of both genderswith confirm diagnosis of diplegic cerebral palsy
  • Patients could ambulate functionally
  • Patients having limited or no prior exposure to NDT
  • Individuals with mild to moderate diplegic cerebral palsy, based on established classification scales (GMFM grade I-III)

Exclusion Criteria

  • Patients with other motor or sensory dysfunctions and unable to understand and obey commands
  • Patient undergone any orthopedic surgery that was ought to treatspasticity
  • Patients with spasticity level 4-5 according to Modified Ashworth Scale
  • Patients with Botulinum toxins type A injection within last 6 months

Outcomes

Primary Outcomes

Modified Ashworth Scale

Time Frame: 9 months

UMN syndrome's component of spasticity is an increase in muscular stretch out reflexes that is velocity-dependent and accompanied by an increase in muscle tone. Bryan Ashworth developed the Ashworth Scale in 1964 while treating patients with MS as a way to grade spasticity. The original Ashworth scale, which rated spasticity on a scale of 0 to 4, classified it as either having no resistance or having limbs that were stiff in flexion or extension. They added 1+ to the scale to boost sensitivity(Bohannon \& Smith, 1987). Muscle spasticity is rated using the modified Ashworth scale score ranging from 0 to 4, having total 6 grades

Gross Motor Function Measure

Time Frame: 9 months

Each item is rated on a four-point ordinal system of assessment. A score of 0 means the task cannot be performed, a score of 1 means the task is able to be started (10% completion), a score of 2 means the task may be completed partially (10% to 100% completion), and a score of 3 means the task is capable of being finished.Every unobserved item on the GMFM-88 receives a score of 0. On the contrast, GMFM-66, however, items that were not seen received a "not tested" or "missing" score.Both versions of GMFM has an excellent reliability

Cerebral Palsy Quality of Life Questionnaire for Children and Adolescent

Time Frame: 9 months

The Cerebral Palsy Quality of Life for Children (CP QOL-Child) is the very first quality of life survey founded on the International Classification of Function (ICF) created particularly for kids with CP.The CP QOL-Child is available in two versions: the main caregiver-proxy report version (proxy version) for kids ages 4 to 12 and a self-report version for kids ages 9 to 12. The CP QOL-Child's internal consistency, test-retest reliability, and construct validity have all been proven to be reliable and valid.

Secondary Outcomes

  • Manual Muscle Testing(9 months)

Study Sites (1)

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