Selective Versus Stepwise Removal of Deep Carious Lesions in Permanent Teeth Using Different Medicaments
- Conditions
- Caries Arrested
- Interventions
- Procedure: partial caries removal
- Registration Number
- NCT06585436
- Lead Sponsor
- Al-Azhar University
- Brief Summary
The study involved 54 adult patients between the ages of 18 and 50 years who had a posterior permanent tooth with a deep occlusal (Class I) carious lesion that extended to the inner third of the dentin (D3) and divided them into two equal groups randomly (N=27) according to the caries removal technique: group 1 (SE), and group 2 (SW). Then each main group was equally subdivided into three equal subgroups (n=9) according to the applied dentin dressing material as follows: Subgroup 1: Nano-silver compound (NSC), Subgroup 2: Chitosan-loaded nano hydroxy apatite (CS/N-HAp), Subgroup 3: Bioactive glass ionomer (N-BAG/GIC). At the first visit both groups received the same treatment of incomplete caries excavation, application of dentin dressing materials and sealing temporarily for 3-months with a glass ionomer cement (GIC). At the second visit the GIC reduced pulpally in (SE) group leaving 2 mm as base and completely removal the remaining carious lesion in (SW) group then re-application of same dentin dressing material on each tooth and GIC as a base. Finally, all cavities were restored with selective enamel etching technique, after which self-etch adhesive and Nano-filled composite resin are applied according to manufacturer instructions. The clinical and digital radiographic evaluations of the success and failure rates were performed at: baseline (7 days), 3, 12, and 18-months.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 54
- Patients with first and second molars with occlusal deep carious lesions (Class I) extending to the inner third of dentin thickness on radiographic examination using (i-sensor H1, Woodpecker, China).
- Teeth with a healthy response to the electrical pulp tester (DY 310, Denjoy Dental CO., LTD, China).
- Teeth with the absence of spontaneous pain.
- Teeth with a negative sensitivity to percussion.
- Teeth with the absence of periapical lesions by a digital radiographic examination.
- Clinically, all teeth were without any mobility.
- Patients who will complete the procedure of follow up.
- Patients who will sign the consent.
- Mutilated teeth or teeth with caries extending subgingivally.
- Teeth with the existence of previous restorations.
- Teeth with periodontal disease, any swelling, fistulas, signs of irreversible pulpitis or necrotic pulp.
- Teeth with roots showing external or internal resorption.
- Pregnant women.
- Presence of any systemic disease.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description selective removal (chitosan loaded nano hydroxyapatite ) partial caries removal selective removal then apply chitosan loaded nano hydroxyapatite selective removal (nano bioactive glass/GIC) partial caries removal selective removal then apply (nano bioactive glass/GIC) selective removal (nanosilver) partial caries removal selective removal then apply (nanosilver) stepwise removal (chitosan loaded nano hydroxyapatite ) partial caries removal stepwise removal then apply (chitosan loaded nano hydroxyapatite ) stepwise removal (nano bioactive glass/GIC) partial caries removal selective removal (nano bioactive glass/GIC) stepwise removal (nanosilver) partial caries removal selective removal then apply (nanosilver)
- Primary Outcome Measures
Name Time Method post operative pain 18 months evaluation of the post operative pain following restorations using modified USPHS
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Al Azhar university
🇪🇬Cairo, Egypt