Study of the Colonic Carriage of Staphylococcus Aureus in a Prospective Cohort of Patients Undergoing Endoscopic Screening for Digestive Cancer in the University Hospital of Saint-Etienne.
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 112
- Locations
- 2
- Primary Endpoint
- Number of patient with Staphylococcus aureus colonic carriage
Study Overview
Brief Summary
Epidemiological study aiming to describe the carriage (nasal, throat, groin, rectal and colonic) of S. aureus in patients without chronic digestive disease who are going to have a colonoscopy for cancer screening. The carriage will be analyzed globally and the similarity of strains isolated from each site will be analyzed using molecular tools. The aim of this study is to better estimate the digestive reservoir of S. aureus to better prevent endogenous infections due to this bacterium.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patient affiliated to French social security
- •Written consent of the patient
- •Patient needing a colonoscopy in the University Hospital of Saint-Etienne, France
Exclusion Criteria
- •Patient who decline to participate to the study
- •Patient in the incapacity to give consent
- •Patient receiving treatment with anticoagulant or antiaggregant platelets
- •Patients with a known haemostatic disorder
- •Pregnant woman
- •Patients with a chronic disease of the gastrointestinal tract
- •Patients receiving long-term corticosteroid
- •Patient receiving anti staphylococcal antibiotics
Arms & Interventions
Patients undergoing a colonoscopy
Staphylococcus aureus carriage is measured in nose, throat, colon, rectum and groin
Intervention: Staphylococcus aureus carriage (Other)
Outcomes
Primary Outcomes
Number of patient with Staphylococcus aureus colonic carriage
Time Frame: Day 1
Staphylococcus aureus carriage in the colon is measured by biopsy
Secondary Outcomes
- Number of patient with Staphylococcus aureus carriage in the nose(Day 1)
- Number of patient with similar Staphylococcus aureus strains in the nose and in the rectum(Day 1)
- Number of patient with Staphylococcus aureus carriage in the throat(Day 1)
- Number of patient with Staphylococcus aureus carriage in the groin(Day 1)