Preventing preterm birth in Chinese women with a short cervix in singleton pregnancies

Completed

• Conditions: Cervical insufficiency; Pregnancy and Childbirth; Incompetence of cervix uteri

• Registration Number: ISRCTN18185477
• Lead Sponsor: Prince of Wales Hospital (Hong Kong)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2012-04-16
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 4000

Inclusion Criteria

Women with singleton viable pregnancy undergoing routine morphology ultrasonography at 18 ? 24 weeks found to have a cervix less than 25 mm

Exclusion Criteria

1. Multiple pregnancies
2. Major fetal abnormalities defined as those that are lethal or require prenatal or postnatal surgery
3. Severe intra-uterine growth restriction (IUGR)
4. Cervical dilatation, painful uterine contractions, history of ruptured membranes, or prophylactic surgical cerclage before randomization
5. Patients who are unconscious, severely ill, mentally handicapped or under the age of 16 years

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Preterm rate before 34 weeks

Secondary Outcome Measures

Name	Time	Method
Perinatal morbidities and mortality