Factors That Effect the Gait Speed in Diabetic Individuals Without Neuropathy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 71
- 试验地点
- 1
- 主要终点
- gait speed
研究概览
简要总结
This study planned to investigate the role of potential explanatory factors effecting the speed of gait such as muscle mass, aerobic capacity, physical activity status, cognitive function, blood pressure, and metabolic measures considering age, sex, and education years in diabetic individuals without neuropathy.
详细描述
Type 2 diabetic people will be screened by clinical symptoms of neuropathy and DN4 questionnaire. Among those who did not have neuropathic symptoms or who have DN4 score below 4 will be considered for the study.Then aerobic capacity will be measured by a cycle ergometer and VO2max will be obtained. Weight, body mass index and muscle mass will be measured by bioimpedance analysis. Physical activity status will be determined by International Physical Activity Score (IPAQ). Cognitive function will be evaluated by Mini Mental test. HbA1c and fasting blood glucose will be measured in venous blood after overnight fasting. Blood pressure will be measured in the sitting position after resting from the left arm. Speed of gait will be measured by an accelerometer.Then, the effect of above mentioned factors on speed of gait will be studied.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Individuals with Diabetes Mellitus less than 10 years but longer than 1 year
- •Absence of neuropathic symptoms
- •DN4 questionnaire sore less than 4
排除标准
- •Individuals who had
- •insulin therapy,
- •poor glycemic control,
- •manifesting cardiovascular disease,
- •retinopathy or other visual problems,
- •diabetic neuropathy,
- •nephropathy,
- •cerebrovascular disease,
- •cognitive impairment,
- •heart failure,
- •alcohol or cigarette dependence,
- •chemo/radiotherapy,
- •foot ulcer,
- •orthopedical or surgical problems
- •wheel-chair or any assistive devices for ambulation
- •prominent knee or hip arthritis, prosthesis
结局指标
主要结局
gait speed
时间窗: The gait speed will be measured once within a month after the participants enrolled.
gait speed measured by wearable accelerometer
次要结局
未报告次要终点
研究者
GULIN FINDIKOGLU
Assoc Proffessor, MD, PhD
Pamukkale University