Septic Shock and Delirium Because of rSO2 Abnormalities in Intensive Care Unit Patients (The SAD BRAIN Study)
Completed
- Conditions
- Septic ShockDeliriumRenal Failure
- Interventions
- Other: Observation
- Registration Number
- NCT01836302
- Lead Sponsor
- University of Manitoba
- Brief Summary
Delirium in the ICU is a prevalent problem occurring in up to 80% of ICU patients. A potential cause of delirium in ICU patients could be cerebral hypoxia. Septic shock is associated with high rates of delirium.
The aim of this pilot study is two fold. First, to determine the feasibility and potential challenges of measuring cerebral oxygenation in ICU patients with severe sepsis and septic shock. And second, to see if the incidence and magnitude of cerebral desaturations correlated with ICU acquired delirium as measured by the Confusion Assessment Method (CAM) scores.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 16
Inclusion Criteria
- Over 18
- Diagnosis of septic shock
- Require mechanical ventilation and vasopressor therapy
Exclusion Criteria
- Previous stroke
- Dementia
- Recent Craniotomy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients with Cerebral Desaturation Observation We will compare the primary and secondary outcomes between the patients who experience cerebral desaturations and those that do not. Patients without cerebral desaturation Observation We will compare the primary and secondary outcomes between the patients who experience cerebral desaturations and those that do not.
- Primary Outcome Measures
Name Time Method Incidence of Delirium 28 Days
- Secondary Outcome Measures
Name Time Method Death 28 Days
Trial Locations
- Locations (1)
Health Sciences Center
🇨🇦Winnipeg, Manitoba, Canada