Comparison of the effect of botanical extract mouthwashes of meswak/aloe vera and chlorhexidine on prevention of ventilator-associated pneumonia
- Conditions
- Ventilator-associated pneumonia.
- Registration Number
- IRCT20161014030294N4
- Lead Sponsor
- Arak University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 70
Existence of endotracheal tube through the mouth
Age 16 to 65 years
Mechanical ventilation for at least 72 hours
Absence of lung infection based on the clinical score of the modified lung infection
Lack of sensitivity to plant compounds
Absence of sepsis
Absence of pulmonary thromboembolism
Absence of atelectasis
Absence of inflammatory diseases of the gastrointestinal tract
Absence of severe liver and bile duct diseases
Transfer the patient from the ICU or die before completing the study
Reluctance of the patient's companions to continue the study
Observe the side effects of using mouthwash such as hives, itching and skin rashes
Sudden changes in the patient's clinical condition or respiratory pattern occur
Existence of defects in the patient's immune system
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The rate of ventilator-induced pneumonia. Timepoint: 72 hours and 7 days after the intervention and when the patient is extubated. Method of measurement: Microbiological tests of lung secretions.
- Secondary Outcome Measures
Name Time Method