Comparison between lignocaine jelly versus betamethasone gel applied over endotracheal tube to reduce postoperative sore throat,cough and hoarseness of voice.
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Incidence of postoperative sore throat, cough and hoarseness of voice after endotracheal intubation.
研究概览
简要总结
Many of the general anaesthetic procedures in the modern anaesthesia practices are carried out with endotracheal intubation. It has advantages including the provision of the reliable airway, prevention of aspiration and smooth delivery of anaesthetic gases. All patients who were intubated for long duration or short duration operations had some degree of airway injury. Common adverse effects of cuffed endotracheal tube-like local irritation, inflammation of the airway mucosa etc leads to post-extubation morbidities such as sore throat, cough and hoarseness of voice which is extremely distressing to the patient. This study will be done to compare the efficacy of betamethasone gel andlignocaine jelly as lubricants in reducing post-operative sore throat, cough and hoarsenessof voice in patients operated under general anaesthesia with endotrachealintubation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade I, II, III
- •Elective procedures requiring endotracheal intubation.
排除标准
- •ASA grade IV & V
- •Patient with history of adverse drug reaction to study medications
- •Pregnant and lactating women
- •Patients having upper respiratory tract infections and oronasal surgeries
- •Anticipated difficult airway
- •Vocal cord pathology.
结局指标
主要结局
Incidence of postoperative sore throat, cough and hoarseness of voice after endotracheal intubation.
时间窗: Immediately after extubation, 1 hours,4 hours, 6 hours,12 hours, 24 hours, 36 hours, and 48 hours.
次要结局
- To see the hemodynamic response(For 2 hours)
研究者
Dr Rajlakshmi
BJ Medical college Ahmedabad