Nicotine and Cannabis Vape Labeling Experiment - Spring 2025

Not Applicable

• Conditions: Vaping; Adolescent; Electronic Cigarette Use; Nicotine; Cannabis

• Registration Number: NCT06919276
• Lead Sponsor: University of Southern California

Brief Summary

This study assesses how the ways in which nicotine and cannabis vaping devices are labeled impact use susceptibility, anticipated effects, and health harm.

Detailed Description

The primary objectives of the study: (1) Determine whether different device labels with the contained substance (nicotine or cannabis) affect adolescent use susceptibility, anticipated effects or impairment, and perceived health harms; (2) Determine whether device color/product flavor differentially impact the study outcomes.

Study Timeline

• Study First Submitted: 2025-02-28
• Study Start: 2025-03-03
• Status Verified: 2025-04
• Study First Submitted QC: 2025-04-04
• Last Update Submitted: 2025-04-04
• Study First Posted: 2025-04-09
• Last Update Posted: 2025-04-09
• Primary Completion: 2025-05
• Study Completion: 2025-06

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 3900

Inclusion Criteria

• Participants must be enrolled in a partnering high school.

Exclusion Criteria

• Participants who cannot independently understand study consent and the study surveys are ineligible.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Use Intention Susceptibility	5 minutes	This 3-item self-report measure assesses participant interest in trying the vaping device in the future. A 4-level Likert scale is used: definitely not, probably not, probably yes, definitely yes.
Perceived Health Harms	5 minutes	This 2-item self-report measure assesses participant perception of health harms and risks associated with using the vaping product. A 4-level Likert scale is used: definitely not, probably not, probably yes, definitely yes.
Anticipated Subjective Effects	5 minutes	This 9-item self-report measure assesses anticipated subjective effects from using the vaping device. Participants will select all that apply.
Anticipated Impairment/Enhancement	5 minutes	This 4-item self-report measure assesses participant anticipated enhancement or impairment effects on completing different activities due to using the vaping product. A 5-level Likert scale is used: definitely make it harder, probably make it harder, no effect, probably make it easier, definitely make it easier.

Trial Locations

Locations (1)

University of Southern California; 🇺🇸 Los Angeles, California, United States