WSI Ratio as a Biomarker for Mechanical Complication of Hemorrhagic MI
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Wall Strain Index for Potential Detection of Intramyocardial Hemorrhage
研究概览
简要总结
Hemorrhagic Myocardial infarctions are at high risk for mechanical complications including cardiac rupture. Prediction of vulnerable myocardial segments is an important step for the stratification of hemorrhagic MI patients. Wall motion index ratio is an important parameter to determine regions of high vulnerability within the 17-segment LV model of hemorrhagic MI.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 79 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Index STEMI
- •Primary PCI
- •Able to complete Cardiac MR - STRAIN Protocol
排除标准
- •Contraindication to CMR (Contrast Hypersensitivity, Metallic Implants, Abnormal Rhythms, breathing difficulties)
结局指标
主要结局
Wall Strain Index for Potential Detection of Intramyocardial Hemorrhage
时间窗: 48 hours Post-PCI
Difference in Wall Strain Index values between patients with intramyocardial hemorrhage and those without, confirmed by cardiac MRI.
Wall Strain Index in Detecting the Severity of Intramyocardial Hemorrhage
时间窗: 48 hours Post-PCI
Relationship between initial Wall Strain Index measurements and the volume of intramyocardial hemorrhage quantified by cardiac MRI
Wall Strain Index Ratio in Identification of Vulnerable LV Segments for Cardiac Rupture
时间窗: 48 hours Post-PCI
Wall Strain Index Ratio for circumferential and longitudinal strain in identifying vulnerable hemorrhagic left ventricular segments at risk for rupture
次要结局
未报告次要终点
研究者
Rohan Dharmakumar
Executive Director, Krannert Cardiovascular Research Center
Indiana University School of Medicine