Double blind randomized placebo controlled study by virtual histology on the influence of oral pioglitazone for 9 month on the development of coronary plaques in non-diabetic patients with coronary heart disease

Med. Klinik / Kardiologie der Med. Fakultät Carl Gustav Carus an der Technischen Unversität Dresden0 个研究点开始时间: 2006年9月5日最近更新: 2012年3月19日

试验速览

暂无简介。

•Instable Angina pectoris or non-ST-elevation myocardial infarction; hemodynamic relevant stenosis >75% of the left coronary artery system; additional stenosis < 50% of the left coronary artery system; age between 18 and 80 years; written informed consent.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•Acute ST-elevation myocardial infarction; diabetes mellitus type I or II; systemic infection; acue or chronic inflammatory disease; sensitivity to Pioglitazone or thiazolidinediones (TZD); severe or multiple allergies; reduction of life expectancy below 12 month; myopathy; heart failure NYHA I to IV; severe organic diseases, cancer, glaucoma, historyof macula oedema, alcohol or drug abuse; pregnancy or brest feeding; blood donor witin last 30 days; previous treatment with TZDs.

发起方

Med. Klinik / Kardiologie der Med. Fakultät Carl Gustav Carus an der Technischen Unversität Dresden