Blood Nitrate/Nitrite Concentrations Following Acute Ingestion of Resync in Men and Women
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Change in systolic blood pressure from daily baseline with 15g Resync
研究概览
简要总结
This study evaluates acute ingestion of the dietary supplement Resync on blood nitrate/nitrite concentrations in a sample of men and women. This will be a crossover trial in which participants take all 4 conditions: 1) 7.5g Resync, 2) 15g Resync, 3) 20g Resync+collagen, 4) placebo.
详细描述
The product known as Resync contains a blend of nitrate-rich foods including beetroot, red spinach, turmeric, ginger root, and aronia berry extracts. Resync is sold commercially and marketed as an ergogenic aid and/or exercise recovery aid. Manufacturers of Resync recommend users take this product 60-90 minutes before an athletic event or 30-90 minutes after exercise. Resync bases these claims on prior studies investigating the individual ingredients' abilities to increase blood nitrate/nitrite levels; however, there are no clinical trials on the finished product itself.
The purpose of this pilot study is to determine the impact of acute, single ingestion of Resync products on blood nitrate/nitrite concentration in a sample of men and women. This will be a crossover trial in which participants take all 4 conditions: 1) 7.5g Resync, 2) 15g Resync, 3) 20g Resync+collagen, 4) placebo.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
盲法说明
Single-Blind
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI 18 - 29.9 kg/m2
- •Non-smoker
- •Non-vegan
- •Not using nitrate-based dietary supplements
排除标准
- •Diagnosed history of diabetes
- •Diagnosed history of cardiovascular disease
- •Diagnosed history of neurological disease
- •Pregnant females
结局指标
主要结局
Change in systolic blood pressure from daily baseline with 15g Resync
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily systolic blood pressure with supplementation from the daily baseline systolic blood pressure with 2 servings (15g) of Resync. Resync powder will be mixed with 12oz of water.
Change in systolic blood pressure from daily baseline with 20g Resync+Collagen
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily systolic blood pressure with supplementation from the daily baseline systolic blood pressure with 1 serving (20g) of Resync+Collagen. This blend contains approximately 17g of collagen, 2 g of Resync, and 1g carbohydrates. Resync+Collagen powder will be mixed with 12oz of water.
Change in blood nitrate+nitrite levels from daily baseline with 7.5g Resync
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily blood nitrate+nitrite from the daily baseline blood nitrate+nitrite with 1 serving (7.5g) of Resync. Resync powder will be mixed with 12oz of water.
Change in blood nitrate+nitrite levels from daily baseline with 15g Resync
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily blood nitrate+nitrite from the daily baseline blood nitrate+nitrite with 2 servings (15g) of Resync. Resync powder will be mixed with 12oz of water.
Change in blood nitrate+nitrite levels from daily baseline with 20g Resync+Collagen
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily blood nitrate+nitrite from the daily baseline blood nitrate+nitrite with 1 serving (20g) of Resync+Collagen. This blend contains approximately 17g of collagen, 2 g of Resync, and 1g carbohydrates. Resync+Collagen powder will be mixed with 12oz of water.
Change in blood nitrate+nitrite levels from daily baseline with placebo.
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily blood nitrate+nitrite from the daily baseline blood nitrate+nitrite with 12oz of food colored water. A red food dye will be used to match coloring of supplements.
Change in systolic blood pressure from daily baseline with 7.5g Resync
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily systolic blood pressure with supplementation from the daily baseline systolic blood pressure with 1 serving (7.5g) of Resync. Resync powder will be mixed with 12oz of water.
Change in diastolic blood pressure from daily baseline with 15g Resync
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily diastolic blood pressure with supplementation from the daily baseline diastolic blood pressure with 2 servings (15g) of Resync. Resync powder will be mixed with 12oz of water.
Change in diastolic blood pressure from daily baseline with 7.5g Resync
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily diastolic blood pressure with supplementation from the daily baseline diastolic blood pressure with 1 serving (7.5g) of Resync. Resync powder will be mixed with 12oz of water.
Change in systolic blood pressure from daily baseline with placebo
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily systolic blood pressure with supplementation from the daily baseline systolic blood pressure with 12oz of food colored water. A red food dye will be used to match coloring of supplements.
Change in diastolic blood pressure from daily baseline with placebo
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily diastolic blood pressure with supplementation from the daily baseline diastolic blood pressure with 12oz of food colored water. A red food dye will be used to match coloring of supplements.
Change in diastolic blood pressure from daily baseline with 20g Resync+Collagen
时间窗: 75-minutes post supplement ingestion
We will determine the change in daily diastolic blood pressure with supplementation from the daily baseline diastolic blood pressure with 1 serving (20g) of Resync+Collagen. This blend contains approximately 17g of collagen, 2 g of Resync, and 1g carbohydrates. Resync+Collagen powder will be mixed with 12oz of water.
次要结局
- Change in heart rate from daily baseline with 15g Resync(75-minutes post supplement ingestion)
- Change in heart rate from daily baseline with placebo(75-minutes post supplement ingestion)
- Change in heart rate from daily baseline with 7.5g Resync(75-minutes post supplement ingestion)
- Change in heart rate from daily baseline with 20g Resync+Collagen(75-minutes post supplement ingestion)
研究者
Richard Bloomer
Dean of School of Health Studies
University of Memphis