Investigating the therapeutic effect of statin relative to the N-acetyl cysteine in the treatment of Helicobacter pylori patients
- Conditions
- Helicobacter pylori patients.
- Registration Number
- IRCT20231017059756N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 180
Informed written consent
Helicobacter pylori positive patients with definitive diagnosis by stool HP antigen test referring to Ghaem Hospital
Age category 18 years and above
Canceling the continuation of the plan
pregnancy
breastfeeding
Weight loss of more than 5% over the past six months
Dysphagia and positive personal or family history of gastrointestinal malignancy
Receiving statin and NAC during the last 6 months
Having a history of gastric surgery
Receiving PPI and antibiotics in the past month
The presence of known drug sensitivity to any of the drugs used
Known liver problems
The presence of obvious gastrointestinal bleeding
Occurrence of possible drug side effects due to drug intervention and possible myopathy due to statin use
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Helicobacter pylori infection recovery rate. Timepoint: Before starting treatment and one month after starting treatment. Method of measurement: Based on Helicobacter pylori antigen test in stool exam.
- Secondary Outcome Measures
Name Time Method