JPRN-UMIN000007065招募中未知
Phase 2 study of bevacizumab and irinotecan as second-line therapy in patients with advanced colorectal cancer previously treated with oxaliplatin and bavacizumab - Bevacizumab Beyond Progression Plus Irinotecan trial
Toyama Prefectural Central Hospital Department of Gastroenterology0 个研究点目标入组 33 人开始时间: 2012年1月16日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 33
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 ot applicable（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •(1)Previously irinotecan treatment (2)Administering transfusion/hematopoietic factor or antithrombotic drug within 14 days (3)Serious renal dysfunction (4)Serious drug hypersensitivity or a history of drug allergy (5)Active concomitant malignancy (6)Uncontrolled infection (7)Symptomatic or asymptomatic but treated heart disease (8)History of thrombosis,interstitial pneumonitis,pulmonary fibrosis or high-grade pulmonary emphysema (9)Fresh hemorrhage from digestive tube,intestines tube paralysis,intestinal obstruction and peptic ulcer (10)Pleural effusion,peritoneal fluid and pericardial fluid (11)Symptomatic brain metastasis (12)History of mental disturbances or cerebrovascular accident (13)high blood pressure and diabetic that cannot be controlled (14)Uncontrolled diarrhea (15)Serious non-healing wound and/or major surgical procedure within 4weeks prior to enroll in this study (16)Traumatic fracture of unrecovery (17)Bleeding tendency and anti-platelets therapy (18)Pregnant women,possibly pregnant women,wishing to become pregnant,and nursing mothers (19)Need to treatment with atazanavir sulfate (20)Paralyzed bowel (21)Other conditions not suitable for this study
研究者
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