跳至主要内容
临床试验/CTRI/2025/03/081991
CTRI/2025/03/081991尚未招募不适用

TO COMPARE THE EFFICACY OF ACETIC ACID EAR DROPS VERSUS CIPROFLOXACIN EAR DROPS IN ACHIEVING DRY EARS IN ACTIVE TUBOTYMPANIC CHRONIC OTITIS MEDIA

KARTHIKA RAJENDRAN1 个研究点 分布在 1 个国家目标入组 94 人开始时间: 2025年4月15日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
94
试验地点
1
主要终点
acetic caid ear drops in efficient in achieving dry ears in chronic otitis media than ciprofloxacin ear drops

研究概览

简要总结

The study is on the role of topical acetic acid in comparision with topical ciprofloxacin ear drops in achieving dry ears in chronic otitis media. The hypothesis of study is  topical acetic acid administration is more effective than topical antibiotics in achieving dry ears in active tubotympa nic type of chronic otitis media. The aim is to compare the efficacy of aural clensing with acetic acid irrigation and topical ciprofloxacin in medical management of active COM tubotympanic type. The objective of study is to evaluate the role of acetic acid application in obtaining dry ears  and to correlate the efficacy of acetic acid application with microbiological culture sensitivity reports.The study will be conducted for a period of 2 years.Patient included in the present study will be distributed in to two groups, group A will recievw topical treatment, irrigation with acetic acid and aural toiletting, group B patients will be treated with topical ciprofloxacin ear drops.Patient will be observed for 2 weeks and at end of 7 th day and 14th day patient will be assessed.

研究设计

研究类型
Interventional

入排标准

年龄范围
15.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Both males and females, 15-60 years Patients with unilateral active tubotympanic chronic otitis media with symptoms more than 4 weeks.
  • Both outpatients and inpatients will be included.

排除标准

  • Patients with Atticoantral types of CSOM disease, cholesteatoma or with marginal perforation of the tympanic membrane.
  • Immunocompromised individuals.
  • Dry ear with CSOM.
  • Serous Otitis Media.
  • CSOM with otomycosis.
  • CSOM with vertigo.
  • Patient on systemic antibiotics or any topical ear drop preparation preceding 2 weeks in group of patients selected for irrigation with acetic acid.

结局指标

主要结局

acetic caid ear drops in efficient in achieving dry ears in chronic otitis media than ciprofloxacin ear drops

时间窗: study will be conducted for a period of 2 years

次要结局

  • To eliminate antibiotic resistance due to repeated usage(To eliminate antibiotic resistance due to repeated usage)
  • To evaluate the role of acetic acid application in obtaining dry ears in CSOM.(To corelate the efficacy of acetic acid application with microbiological culture sensitivity reports .)

研究者

发起方
KARTHIKA RAJENDRAN
申办方类型
Other [OTHERS (SELF)]
责任方
Principal Investigator
主要研究者

KARTHIKA RAJENDRAN

SRM Medical College Hospital and Research Centre

研究点 (1)

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