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Clinical Trials/NCT02533063
NCT02533063
Completed
N/A

Semi-Recumbent Vibration Therapy in Older Adults

University of Wisconsin, Madison1 site in 1 country32 target enrollmentNovember 2015
ConditionsSarcopeniaAging

Overview

Phase
N/A
Intervention
Not specified
Conditions
Sarcopenia
Sponsor
University of Wisconsin, Madison
Enrollment
32
Locations
1
Primary Endpoint
Weight Corrected Jump Power Based on Participant's Jump on the Jump Force Plate
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

This proposed prospective study will evaluate whether a novel exercise approach, seated vibration therapy, can improve function in the target population of older adults. Therefore, the primary aim of this pilot is to examine the effect of vibration therapy on muscle function (balance, muscle power and strength) and muscle mass.

Detailed Description

There are four study visits; screening/baseline followed by eight weeks of training three times a week, visit 1 at eight weeks followed by 4 weeks of washout, Visit 2 at 12 weeks followed by eight weeks of training three times a week, and a final Visit 3 at 20 weeks. At the screening visit, volunteers will be asked to perform tests included in the short physical performance battery (SPPB) (gait speed, chair rise, balance). If the participants score is ≤ 9 or ≤ 2 in any of the three tests included in the SPPB they will be eligible for the intervention phase. At the baseline visit several questionnaires will be obtained and participants then will proceed with muscle function tests (SPPB, jumping mechanography, grip strength, timed-up-and-go test). Participants will then be randomized into one of two groups. The first group will receive vibration + loading treatment for the first 8 weeks, the second group will receive sham treatment (loading only). After 8 weeks both groups will go through a 4 week wash-out period and then crossover will occur. The first group will now receive sham treatment (loading only) while the second group will receive vibration + loading treatment. The participants will train for 10 minutes, 3 times a week, during the active 16 total weeks.

Registry
clinicaltrials.gov
Start Date
November 2015
End Date
February 15, 2017
Last Updated
7 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Men and women age ≥ 70 years
  • Able and willing to sign informed consent
  • Able to stand without assistance
  • Able and willing to train for 10 minutes, 3 times per week
  • Total SPPB score of ≤ 9 or ≤ 2 in any of the three tests included in the SPPB

Exclusion Criteria

  • Cognitive impairment to the degree that it limits the ability of signing informed consent
  • Unable to sit upright for 10 minutes
  • History of injury or surgery within the prior six months which limits the ability to ambulate
  • Major illness that might cause missed training sessions or visits.

Outcomes

Primary Outcomes

Weight Corrected Jump Power Based on Participant's Jump on the Jump Force Plate

Time Frame: This was collected 4 times: Baseline, after 8 week loading/loading+ vibration training, after 4 week washout, after 8 week crossover training.

The primary aim of this pilot is to examine the effect of vibration therapy on muscle function. Weight corrected jump power will be the main outcome variable. Countermovement jumps are performed on a Leonardo force plate (Novotec Medical, Pforzheim, Germany) following standard procedures. Jumping mechanography uses maximal countermovement jumps to quantitatively measure muscle strength in the legs. Participants will be asked to perform three countermovement jumps. Participants are asked to try to jump as high as possible using both legs. Three jumps are performed; the jump with the highest jump height is used for analysis.

Secondary Outcomes

  • Grip Strength(Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.)
  • Gait Speed(Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.)
  • Short Physical Performance Battery (SPPB)(Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.)
  • Timed-Up-and-Go (TUG)(Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.)
  • Sway(Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.)
  • Bioelectrical Impedance Spectroscopy (BIS)(Measured at Baseline, after Intervention 1, after Washout, and after Intervention 2.)

Study Sites (1)

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