The associations of maternal folic acid intake and folate, vitamin B12 and homocysteine concentrations with dental development in childre
Completed
- Conditions
- folic acid, folate, vitamin B12, teeth, maturation
- Registration Number
- NL-OMON28703
- Lead Sponsor
- The Generation R Study is conducted by the Erasmus University Medical Center in close collaboration with the School of Law and Faculty of Social Sciences of the Erasmus University Rotterdam, the Municipal Health Service Rotterdam area, Rotterdam, the Rotterdam Homecare Foundation, Rotterdam and the StichtingTrombosedienst and ArtsenlaboratoriumRijnmond (STAR), Rotterdam.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 3728
Inclusion Criteria
Mothers with available information on folic acid use and folate , vitamin B12 or homocysteine concentrations; Singleton life born children; Children participating in 9 years follow up measurements
Exclusion Criteria
twin births, children who did not attend follow up visits at the age of 9 years, excluded children without OPG available or bad image
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method dental development in children
- Secondary Outcome Measures
Name Time Method dental development in children