Surgical and Reproductive Results of Fertility-sparing Treatment for Low-grade Endometrial Stromal Sarcoma: A Retrospective Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Low Grade Endometrial Stromal Sarcoma of Uterus (Diagnosis)
- Sponsor
- Lei Li
- Enrollment
- 1000
- Locations
- 1
- Primary Endpoint
- Progression-free survival
- Status
- Recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
This study is to investigate the survival outcomes and fertility outcomes in patients with uterine low-grade endometrial stromal sarcoma (LGESS) treated in Peking Union Medical College Hospital. All primary and recurrent LGESS patients will be enrolled. The study will collect retrospectively data consisting of epidemiological characteristics, surgical, medical treatment and adjuvant therapy. Details about recurrence, mortality, pregnancy and obstetrical outcomes are also followed as primary endpoints. Fertility-sparing procedures, including uterine-sparing and ovary-sparing surgeries will be recorded specifically.
Investigators
Lei Li
Professor
Peking Union Medical College Hospital
Eligibility Criteria
Inclusion Criteria
- •Aged 18 years or older
- •Confirmed of LGESS
- •Acceptance of surgical treatment for LGESS
- •With detailed follow-up outcomes
Exclusion Criteria
- •Not meeting all of the inclusion criteria
Outcomes
Primary Outcomes
Progression-free survival
Time Frame: One year
Progression-free survival after surgery
Pregnancy rate
Time Frame: One year
Pregnancy rate after surgery in patients with fertility-sparing patients
Overall survival
Time Frame: One year
Overall survival after surgery
Secondary Outcomes
- Full-term pregnancy rate(One year)
- Miscarriage rate(One year)