Optimising newborn nutrition during therapeutic hypothermia

Not Applicable

Completed

• Conditions: Hypoxic-ischaemic encephalopathy requiring therapeutic hypothermia; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN47404296
• Lead Sponsor: Imperial College London

Brief Summary

2018 Protocol article in https://pubmed.ncbi.nlm.nih.gov/30355795/ protocol (added 26/11/2020) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34096500/ (added 08/06/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33891879/ Feeding during therapeutic hypothermia (added 06/09/2023) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/33952628/ Parenteral nutrition during therapeutic hypothermia association with higher late-onset infection but lower mortality (added 06/09/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-07-24
• Study Completion: 2019-01-09
• Last Update Posted: 18 September 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 6030

Inclusion Criteria

1. Infants born at 36 gestational weeks or later
3. Received therapeutic hypothermia for Hypoxic Ischaemic Encephalopathy (HIE) for at least 72 hours
3. Died during therapeutic hypothermia

Exclusion Criteria

Infants with missing data for principal background and outcome variables. Missing values for other variables will be dealt with using multiple imputation.

Study & Design

• Study Type: Observational
• Study Design: Not specified