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临床试验/IRCT20191014045107N1
IRCT20191014045107N1招募中2 期

Efficacy of Verapamil in patients with chronic rhinosinositis with nasal polyposis reffered to Hazrat Rasool hospital: Double blind placebo control trial

Iran University of Medical Sciences0 个研究点目标入组 36 人开始时间: 待定最近更新:
适应症

试验速览

阶段
2 期
状态
招募中
入组人数
36

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 years 至 55 years(—)
性别
All

入选标准

  • Patients of Male And Female reffered to Allergy and Clinical Immunology Department of Hazrat e Rasool Center
  • Age between 18-55 years old
  • Diagnosed with Chronic Rhinosinusitis with Nasal Polyps according to the EPOS 2012 consensus criteria; Moderate to Severe (Baseline SNOT-22 Score =20)

排除标准

  • Patients with the following comorbidities: GI Hypomotility, Heart Failure, Liver Failure, Kidney Disease, Muscular Dystrophy, Pregnant or Nursing Females, Hypertrophic Cardiomyopathy, Atrial and ventricular arrhythmia
  • Patients with conductive heart disease like block grade 2 or 3 in EKG
  • Patients taking the following medications; Aspirin, Beta-blockers, Cimetidine, Clarithromycin, Erythromycin, Cyclosporin, Digoxin, Disopyramide, Diuretics, Flecainide, HIV Protease Inhibitors(Indinavir, Nelfinavir, Ritonavir), Quinidine, Lithium, Pioglitazone, Rifampin and systemic corticosteroids one month before trial
  • HR<60 or SBP<110 or DBP<70

研究者

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