Continuous Versus Conventional Volume Management During CRRT (Continuous Renal Replacement Therapy)

Not Applicable

Completed

• Conditions: Continuous Renal Replacement Therapy
• Interventions: Device: use of continuous renal replacement machine for renal replacement; Device: use of blood volume monitoring device in conjunction with machine used for continuous renal replacement to assess and determine volume removal

• Registration Number: NCT01405092
• Lead Sponsor: Dallas VA Medical Center

Brief Summary

Use of on-line blood volume monitoring during continuous renal replacement therapy can improve volume management in acute kidney injury patients requiring renal replacement

Detailed Description

Not available

Study Timeline

• Study Start: 2010-04
• Study First Submitted: 2011-07-28
• Study First Submitted QC: 2011-07-28
• Study First Posted: 2011-07-29
• Status Verified: 2012-08
• Primary Completion: 2012-08
• Study Completion: 2012-08
• Last Update Submitted: 2012-08-07
• Last Update Posted: 2012-08-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 28

Inclusion Criteria

• Patients with kidney injury requiring continuous renal replacement therapy and volume removal

Exclusion Criteria

• unable to provide or obtain patient consent
• not expected to survive 48 hours

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Standard volume management	use of continuous renal replacement machine for renal replacement	patients on this arm will receive usual care volume management during continuous renal replacement therapy
continuous volume management	use of continuous renal replacement machine for renal replacement	use of Critline, Hemametrics USA, in conjunction with continuous renal replacment therapy to determine volume removal
continuous volume management	use of blood volume monitoring device in conjunction with machine used for continuous renal replacement to assess and determine volume removal	use of Critline, Hemametrics USA, in conjunction with continuous renal replacment therapy to determine volume removal

Primary Outcome Measures

Name	Time	Method
compare number of hypotensive events in treatment versus control arms	24 hour for each arm	compare the number of hypotensive events during use of crit-line monitor over 24 hour period versus during control 24 hour period

Trial Locations

Locations (1)

Dallas VA Medical Center; 🇺🇸 Dallas, Texas, United States