NCT01376674已完成不适用
Changes of T-cell-immune-status During Curative Radiotherapy in Prostate Cancer
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- T-cell-immunity in time-course
研究概览
简要总结
Immunological effects of radiotherapy have been described before, but not evaluated in a time-dependant manner.
In order to identify a possible time frame for combination therapies, white blood cells are isolated of samples taken at different time points before during and after standard radiotherapy in patients with localised prostate cancer. The overall activity of the T-cell-system as well as tumor-specific T-cell-response are evaluated.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Localised prostate cancer (node negative)
- •definitive radiotherapy
- •informed consent
排除标准
- •medication including steroids or immunosuppressants
结局指标
主要结局
T-cell-immunity in time-course
时间窗: During and 3-6 months after radiotherapy
次要结局
未报告次要终点
研究者
Franziska Eckert
M.D.
University Hospital Tuebingen
研究点 (1)
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