IRCT20220609055116N1
Not yet recruiting
Phase 2
Clinical assessment of the efficacy of tranexamic acid-niacinamide loaded niosome in comparison to tranexamic acid-niacinamide and hydroquinone conventional creams in melasma
Overview
- Phase
- Phase 2
- Status
- Not yet recruiting
- Enrollment
- 102
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 years to 50 years (—)
- Sex
- All
Inclusion Criteria
- •Patients (Male/female) with melasma between 18 and 50 years old
- •Patients who have had melasma for at least 6 months ago
- •Patients who are capable to understand, read, and write the informed consent form
- •Patients who are able to participate in periodic follow\-up visits by physician
Exclusion Criteria
- •Patients who have received oral contraceptive (OCP) therapy within 3 months prior to the study initiation or during the study
- •Patients who are receiving oral corticosteroids or applying topical corticosteroids on melasma lesions during the study
- •Patients with a history of thyroid disease
- •Patients with a history of intolerance, hypersensitivity reactions, or severe irritation to hydroquinone, tranexamic acid, or niacinamide,
- •Patients with other hyperpigmentary disorders
- •Pregnancy or lactation
- •Patients who have received any pharmacologic or procedural treatment within 2 months prior to the study initiation
Investigators
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