Usefulness of Lung Ultrasound for the Detection of Volume Overload in Patients With Severe Preeclampsia
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 202
- 试验地点
- 1
- 主要终点
- Lung Ultrasound evaluation
研究概览
简要总结
This research aims to evaluate the usefulness of lung ultrasound (LUS) for detecting and monitoring fluid overload in patients with severe preeclampsia. Severe preeclampsia is a leading cause of maternal death and illness worldwide, often causing fluid buildup that can lead to a serious complication called pulmonary edema, especially after delivery.
The study will be a prospective, longitudinal observational study with a diagnostic validation component. It will involve patients with a diagnosis of severe preeclampsia who meet specific inclusion criteria. Each participant will undergo a clinical exam and a lung ultrasound, which will assess eight zones of the lungs. The total number of B-lines-a sign of interstitial edema-will be documented.
Data will be collected at three key times: upon admission, in the immediate postpartum period (within 24 hours of delivery), and 7-10 days postpartum. The results from the LUS will be compared to clinical signs like shortness of breath, rapid breathing, crackling sounds in the lungs, and oxygen saturation levels.
The expected impact of this research is to provide evidence that LUS is a valuable, non-invasive, and accessible tool for the early detection of pulmonary congestion in patients with severe preeclampsia. This could lead to improved clinical decision-making and a reduction in maternal respiratory complications.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Preeclampsia with severe features.
- •Gestational age 24 weeks - 41 weeks.
排除标准
- •Chronic lung disease.
- •Known heart disease.
- •Diagnosis of lung edema at admission
- •Body mass index > 40
- •Need for immediate delivery
结局指标
主要结局
Lung Ultrasound evaluation
时间窗: One evaluation at admission, another one just before delivery and a final one 24 hours after delivery
Three or more B Lines in at least two lung zones using lung ultrasound
次要结局
- Dyspnea(Report of the symptom by the patient from admission for up to three days)
- Tachypnea(Report of the symptom from admission for up to three days.)
- Oxygen saturation(Report of the value measured by a pulse oxymeter from admission for up to three days)
研究者
Osvaldo A. Reyes T.
Head of Research Department
Saint Thomas Hospital, Panama
