Multi-center clinical trial of a Carbon-ion radiation therapy for unresectable and local therapy unsuitable hepatocellular carcinoma

Ohno Tatsuya0 个研究点目标入组 130 人开始时间: 2020年5月22日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1) Histologically or clinically diagnosed primary hepatocellular carcinoma.
•2) Untreated and absence of previous local therapy.
•3) Solitary tumor without extrahepatic lesions.
•4) The tumor is measurable and tumor size is less than 12 cm.
•5) Absence of major portal vein and/or hepatic vein.
•6) The tumor is in contact with the alimentary tract.
•7) Unfit for resection or liver transplantation.
•8) Unfit for percutaneous tumor ablation.
•9) ECOG PS: 0-2.
•10) Child-Pugh score of the patient is from 5 points to 9 points.
•11) Absence of uncontrolled ascites and/or pleural effusion.
•12) 20-year-old or older.
•13) The patient is able to understand the explanation of the clinical trial and written informed concent is obtained.

•1) Patients with any other active malignancies.
•2) Having esophageal varices which are at great risk of bleeding
•3) Having active infectious diseases
•4) Having a fever greater than 38 degrees Celsius.
•5) Having myocardial infarction or angina pectoris within 6 months.
•6) Having interstitial pneumonitis, pulmonary fibrosis or severe respiratory disease such as pulmonary emphysema.
•7) Having radiation hypersensitivity.
•8) Associated with mental illness or manifestation complicating study participation.
•9) Being pregnant or possible conception.
•10) Miscellaneous inappropriate conditions judged by physicians.

发起方

Ohno Tatsuya