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临床试验/NCT01075334
NCT01075334Unknown不适用

Is a Carnitine Based Food Supplement (PorimoreTM) for Infertile Men Superior to Folate and Zinc With Regard to Pregnancy Rates in Intrauterine Insemination Cycles?

Shaare Zedek Medical Center2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2010年2月最近更新:
适应症

试验速览

阶段
不适用
入组人数
100
试验地点
2
主要终点
Pregnancy Rate

研究概览

简要总结

Many cases of male infertility are poorly understood and regarded as unexplained. Therefore, a etiological treatment for this condition can not be offered in most cases. A beneficial effect on sperm motility was found in trails using antioxidants such as carnitine, zinc and folic acid. However, most studies lacked a sufficient power to detect a significant effect on pregnancy rates. In this study, infertile men with abnormal sperm quality parameters will be randomized to receive either carnitine-based food supplement (Porimore) or folate and Zinc Tablets.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 50 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • infertility
  • at least one abnormal sperm quality parameter
  • female age < 35
  • normal ovarian reserve

排除标准

  • known allergy to one of the food additives planned for treatment

结局指标

主要结局

Pregnancy Rate

时间窗: 3 Insemination cycles

proportion of women becoming pregnancy following treatment with intrauterine insemination

次要结局

  • Sperm quality parameters(3 months)

研究者

申办方类型
Other

研究点 (2)

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