NCT01075334Unknown不适用
Is a Carnitine Based Food Supplement (PorimoreTM) for Infertile Men Superior to Folate and Zinc With Regard to Pregnancy Rates in Intrauterine Insemination Cycles?
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Pregnancy Rate
研究概览
简要总结
Many cases of male infertility are poorly understood and regarded as unexplained. Therefore, a etiological treatment for this condition can not be offered in most cases. A beneficial effect on sperm motility was found in trails using antioxidants such as carnitine, zinc and folic acid. However, most studies lacked a sufficient power to detect a significant effect on pregnancy rates. In this study, infertile men with abnormal sperm quality parameters will be randomized to receive either carnitine-based food supplement (Porimore) or folate and Zinc Tablets.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 50 Years(Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •infertility
- •at least one abnormal sperm quality parameter
- •female age < 35
- •normal ovarian reserve
排除标准
- •known allergy to one of the food additives planned for treatment
结局指标
主要结局
Pregnancy Rate
时间窗: 3 Insemination cycles
proportion of women becoming pregnancy following treatment with intrauterine insemination
次要结局
- Sperm quality parameters(3 months)
研究者
研究点 (2)
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