跳至主要内容
临床试验/CTRI/2024/04/066393
CTRI/2024/04/066393尚未招募不适用

A Randomized Observational Study to determine the minimum effective volume of Local Anesthetic Needed for Ultrasound Guided Supraclavicular Brachial Plexus Block

Neha Jha1 个研究点 分布在 1 个国家目标入组 138 人开始时间: 2024年5月6日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
138
试验地点
1
主要终点
To estimate the minimum effective volume of LA for ultrasound guided supraclavicular block

研究概览

简要总结

For upper limb surgery, supraclavicular block offers excellent anesthetic [1,2]. Additionally, the use of ultrasound guiding during supraclavicular block has been developed and is growing in acceptance [3]. Numerous benefits of ultrasound-guided supraclavicular block include higher success rates, quicker onset times, and less problems [4-6]. The possibility of using less local anesthetic was shown in earlier investigations on ultrasound-guided axillary blocks and interscalene blocks [7–10]. However, there is significant debate regarding the ultrasound-guided supraclavicular block’s use of a lower anesthetic amount [11,12].

The Dixon and Massey up and down method (DUDM) and biased coin design up and down method (BUDM) were used to calculate the minimum effective volumes (MEV) 50, MEV90, and MEV95, respectively, in previous studies on the minimum effective volume for the ultrasound-guided supraclavicular block [11,12]. Statistics was used to estimate these effective amounts. The comparison of the various anesthetic volumes in the clinical practice for the ultrasound-guided supraclavicular block has not been explored, and Orebaugh et al. [13] noted that the results from the DUDM may differ from those of the actual practice.

This study’s objective is to analyse clinical data in relation to different local anesthetic dosages used during an ultrasound-guided supraclavicular block.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • American Society of Anaesthesiologists physical status I-II
  • Patients schedule for upper limb surgery
  • Ultrasound visibility score equal or greater than 10.

排除标准

  • ASA III and IV
  • Pregnant Patients
  • Patients with coagulation disorders.

结局指标

主要结局

To estimate the minimum effective volume of LA for ultrasound guided supraclavicular block

时间窗: Baseline, 15 min, 30 min, 45 min, 60min, 75 min, 90 min, 105 min, 120 min, 135 min, 150 min.

次要结局

  • 1. To study onset time for sensory block(2. To study onset time for motor block)

研究者

发起方
Neha Jha
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Neha Jha

BJGMC and SGH Pune

研究点 (1)

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