IRCT20140818018842N37招募中2 期
Comparison of high dose versus low dose of fluconazole for primary prevention of candida infections in patients with hematological malignancies, A single blind prospective randomized clinical trial
Research Institute for Oncology, Hematology and Cell Therapy0 个研究点目标入组 120 人开始时间: 待定最近更新:
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 120
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •Age above 18 years
- •All patients with hematological malignancies can receive a prophylactic regimen against Candida, including: Patients with acute leukemia undergoing primary induction or salvage chemotherapy with the possibility of developing Mucositis
- •Patients with acute leukemia or Myelodysplastic syndromes (MDS) who are expected to experience severe and fatal neutropenia (ANC<500 for more than 7 days) following chemotherapy
- •Having the informed consent of the patient to participate in the study
排除标准
- •Patients with history of idiosyncratic hypersensitivity reaction to azoles
- •Patients with disturbed liver tests with transaminases more than 10 times the normal limit
- •Life expectancy less than 3 weeks
- •History of treatment with systemic antifungal drugs in the last two weeks
- •Patients who have been diagnosed with a fungal infection and are suffering from a fungal infection
- •Patients with increased QTc interval or Torsades de pointes
- •Patients receiving drugs with major clinical interaction (category X) with fluconazole
- •Having a history of invasive fungal infection requiring systemic treatment in the last 6 months
- •Failure to receive fluconazole for more than 3 days during the study
- •Patients with renal failure as CrCl =50 mL/min
- •breastfeeding
研究者
相似试验
招募中
3 期
Comparison of the effect of fluocinolone drug with oral atorvastatin on the treatment of patients with vitiligoIRCT20151228025732N64Semnan University of Medical Sciences40
已完成
3 期
Comparison of low dose and high dose of furazolidone in the treatment of Helicobacter pylori infectioGastric ulcerHelicobacterpylori Eradication.IRCT20160118026097N6Gorgan University of Medical Sciences170
已完成
2 期
Comparison of two regimens of fluconazol in treatment of cutaneous lieshmaniasisCutaneous leishmaniasis.Cutaneous leishmaniasisIRCT138710221542N1Shiraz University of Medical Scienses94
已完成
2 期
Comparison of the efficacy of oral fluconazole and oral Terbinafine in the treatment of moderate to severe seborrheic dermatitisSeborrhoeic dermatitis.Seborrhoeic dermatitisIRCT201102205871N1Gilan University of Medical Sciences64
进行中（未招募）
不适用
A dose-ranging study of fluticasone furoate (FF) inhalation powder in children aged 5-11 years with asthmaChronic disease of the lungs characterized by airway inflammation,bonchoconstriction and increased airway responsiveness.MedDRA version: 16.1Level: PTClassification code 10003553Term: AsthmaSystem Organ Class: 10038738 - Respiratory, thoracic and mediastinal disordersEUCTR2011-003338-15-DEGlaxoSmithKline Research and Development Limited575