Risk factors for blood requirement in coronary artery bypass surgery

Phase 4

Not yet recruiting

• Conditions: Atherosclerotic heart disease of native coronary artery,

• Registration Number: CTRI/2019/04/018756
• Lead Sponsor: Kasturba Medical Collage and Hospital

Brief Summary

Hospital Research EthicsCommittee approval will be obtained. Data of all patients who had undergoneelective off pump CABG will be obtained from hospital record section. Patientswho had undergone emergency CABG surgeries, combined surgeries like CABG withMVR or CABG with AVR and on pump CABG are excluded from study. Preoperativeinvestigations like CBC, renal functions, coagulation profile etc. will becollected from hospital laboratory reports.

Pre-operative parametersanalyzed will include age, sex, body surface area (BSA), left main coronaryartery stenosis >50%, antiplatelet medications within 7 days before operation,pre-operative heparin therapy, recent history of myocardial infarction (within6 months), ejection fraction , previous cardiac surgery, chronic renal failure,cerebrovascular disease, antifibrinolytic drugs and last preoperative Hct.Intraoperative data consisted of number of distal anastomoses performed, use ofinternal mammary arteries (IMA), and lowest intraoperative Hct documented.

 The primary endpointsof interest will be packed red blood cell transfusions, reoperation rate forbleeding or cardiac tamponade and total postoperative chest tube drainage. Onlyintraoperative and postoperative homologous packed RBC transfusions will berecorded.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2019-04-18
• Study Start: 2019-04-30

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 142

Inclusion Criteria

• Off pump CABG surgeries 2.
• Elective CABG.

Exclusion Criteria

• Emergency CABG 2.
• Patients undergoing combined surgeries like CABG + AVR or CABG + MVR 3.
• On pump CABG.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Packed red blood cell transfusions intraoperatively.	Six days
2. Reoperation rate for bleeding or cardiac tamponade	Six days

Secondary Outcome Measures

Name	Time	Method
1. Total chest tube drain	2. Total number of blood transfusions

Trial Locations

Locations (1)

Kasturba Medical Collage and Hospital; 🇮🇳 Udupi, KARNATAKA, India

Kasturba Medical Collage and Hospital

🇮🇳Udupi, KARNATAKA, India

Dr Vijayakumara

Principal investigator

8970213332

vijaysd84@gmail.com