Predictors of packed red blood transfusion in patients undergoing off pump coronary artery bypass graft surgery

Hospital Research EthicsCommittee approval will be obtained. Data of all patients who had undergoneelective off pump CABG will be obtained from hospital record section. Patientswho had undergone emergency CABG surgeries, combined surgeries like CABG withMVR or CABG with AVR and on pump CABG are excluded from study. Preoperativeinvestigations like CBC, renal functions, coagulation profile etc. will becollected from hospital laboratory reports.

Pre-operative parametersanalyzed will include age, sex, body surface area (BSA), left main coronaryartery stenosis >50%, antiplatelet medications within 7 days before operation,pre-operative heparin therapy, recent history of myocardial infarction (within6 months), ejection fraction , previous cardiac surgery, chronic renal failure,cerebrovascular disease, antifibrinolytic drugs and last preoperative Hct.Intraoperative data consisted of number of distal anastomoses performed, use ofinternal mammary arteries (IMA), and lowest intraoperative Hct documented.

 The primary endpointsof interest will be packed red blood cell transfusions, reoperation rate forbleeding or cardiac tamponade and total postoperative chest tube drainage. Onlyintraoperative and postoperative homologous packed RBC transfusions will berecorded.