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临床试验/NCT01600794
NCT01600794暂停不适用

To Evaluate The Androgens and Ovary Function Impact on The Pregnancy Outcome in In Vitro Fertilization

Taipei Medical University WanFang Hospital0 个研究点目标入组 1,000 人开始时间: 2011年10月最近更新:
适应症

试验速览

阶段
不适用
状态
暂停
入组人数
1,000

研究概览

简要总结

Because the society convention is changed, people are late for getting married, leading to increasing the bearing age in women. According to the previous study, if the age is over 30, the oocyte number in ovary has left only 10% and 3% in over 40 years old. The data is collected by Bureau of Health Promotion, Department of Health shows that there are about 7000 people treating the infertility and it spends about 150000 to 250000 NT dollars in every in vitro fertilization (IVF) cycle, but the live birth rate is only 30%. So it is important to know how to estimate and approve the ovary function that lead to increase the live birth rate. The investigators plan to estimate the correlation between the serum androgens levels and pregnancy outcome in the women who have infertility problem. Furthermore, for the repeated IVF cycle, the ovary function might be re-evlauated because of the possible effect from stimulated drugs used on previous cycle. It's important to understand the ovary function for IVF patient to choose the appropriate drugs and dose.

The investigators use blood and clinical test to analyze, the items for analysis are below:

  1. Routine blood test: FSH、LH、E2、P4、Anti-Mullerian Hormone(AMH)、
  2. Studied blood test: Inhibin B、total testosterone (TT)、Androstenedione、DHEA-S
  3. Clinical test: Ultrasound
  4. Personal condition. In order to finishing the test, every patient will be asked to collect about 10 to 15 cc blood for the research.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
20 Years 至 45 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • This study include the patients who are evaluated by the doctors and are sure to process the IVF cycle.

排除标准

  • This study exclude the patients who are not evaluated by the doctors and are not sure to process the IVF cycle.

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ming-I Hsu

Taipei Medical University WanFang Hospital

Taipei Medical University WanFang Hospital

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