Comparison of single-dose preoperative Ibuprofen vs. Ibuprofen with Arginine in the control of postoperative pain in canal treatments

Not Applicable

• Conditions: Arginine; Anti-Inflammatory Agents; Endodontics.; E06.397; D12.125.068.050; D27.505.954.158

• Registration Number: RBR-5tfrhv
• Lead Sponsor: niversidade Estadual de Ponta Grossa

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-11-08
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Men or women between 20 and 59 years of age in good health; Satisfy ASA I or II medical history according to the American Society of Anesthesiologists; Need for endodontic therapy in uni or multi-root teeth, asymptomatic with necrotic pulp; Volunteers who can provide informed consent.

Exclusion Criteria

Men or women under 20 years of age; Pregnant or lactating women; History of allergy or hypersensitivity to ibuprofen, arginine or local anesthetics; Need for antibiotic prophylaxis; Gastrointestinal disorders, esophageal reflux; Active asthma; Decreased hepatic function; Bleeding disorders; Decompensated diabetes mellitus; Ingestion of analgesics and anti-inflammatories in the last 12 hours (as it may exert a therapeutic effect at the time of the study); Intake of alcoholic beverage in the last 24 hours;Individuals classified as class III to V according to the American Society of Anesthesiologists; Individuals unable to provide informed consent.

Study & Design

• Study Type: Intervention
• Study Design: Not specified