Innovative Ultrasound Technology in Neuromuscular Disease
- Conditions
- Amyotrophic Lateral SclerosisRadiculopathyMyopathyMuscular DystrophyPolyneuropathy and MononeuropathiesTrauma InjuryOrthopedic Disorder
- Registration Number
- NCT02104921
- Lead Sponsor
- Beth Israel Deaconess Medical Center
- Brief Summary
This study is utilizing ultrasound measurement to measure neuromuscular disease status in adult patients. The hypothesis is the by quantifying ultrasound data, it is possible that ultrasound can be utilized as a tool to determine if a disease is responding to therapy or progressing.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 223
- History of a well-defined, localized or generalized neuromuscular condition producing weakness or muscle atrophy, including disuse atrophy.
- Multiple generalized neuromuscular conditions.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quantitative ultrasound data, including quantified grayscale data and backscattered acoustic data 1 year Ultrasound data will be collected on multiple muscles in each person. The images will then be quantified using either 1. A grayscale technique in which the images themselves are analyzed via standard image software (e.g., Adobe Photoshop) as to level of echo intensity in a pre-specific region of interest or 2. the raw quantified backscatter data is captured by the transducer, expressed as a unit of power, in the same pre-specified area of interest
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Beth Israel Deaconess Medical Center
🇺🇸Boston, Massachusetts, United States