IRCT20220416054548N1
Recruiting
Phase 2
Determining the association of response rate to Intravitreal injection of bevacizumab and macular vessel density in patients with diabetic macular edema using optical coherence tomography angiography (OCT-A) in outpatients referred to Feyz Hospital
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Esfahan University of Medical Sciences
- Enrollment
- 70
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Age over 18 years
- •Having type 1 or 2 diabetes
- •Central macular edema based on Heidelberg's clinical examination and OCT in one or both eyes (at least 305 µm in women and 320 µm in men)
- •Best modified view less than or equal to 10/7
- •No history of laser in the patient's eye
- •Moderate to severe non\-proliferative diabetic retinopathy with diabetic macular edema
- •Transparent media to the extent that it does not interfere with the quality of images and their analysis (SSI: signal strength index: 37\-40\)
Exclusion Criteria
- •History of retinal vascular obstructive diseases
- •History of intraocular injection in the last 6 months
- •History of intraocular and retinal laser in the affected eye in the last 12 months
- •Decreased vision following any ocular pathology other than diabetic retinopathy
- •High Myopia (\= \-8\)
- •History of eye surgery in the last 6 months
- •Uncontrolled glaucoma (IOP \= 30 mmHg despite maximal treatment)
- •Uncontrolled diabetes
- •Uncontrolled blood pressure (SBP \=180 mmHg or DBP \=100 mmHg
- •Connective tissue diseases
Outcomes
Primary Outcomes
Not specified
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