MedPath

Enhancing Strength Gains With the Power of the Mind

Not Applicable
Recruiting
Conditions
Healthy
Interventions
Behavioral: Elastic Band Training
Behavioral: Elastic Band Training with Maximal Mental Effort
Registration Number
NCT06099678
Lead Sponsor
Kennesaw State University
Brief Summary

The goal of this clinical trial is to determine the effect of maximal mental effort combined with elastic band training on strength and neuromuscular function in healthy, older females. The main questions it aims to answer are:

* Does elastic band training in combination with maximal mental effort increase strength more than elastic band training alone?

* Does elastic band training in combination with maximal mental effort improve neuromuscular function more than elastic band training alone?

Participants will be randomly assigned to 1 of 3 groups:

* Elastic band training

* Elastic band training with maximal mental effort

* Control

Researchers will compare groups to determine differences in changes in strength, neuromuscular function, and body composition.

Detailed Description

Participants in both training groups will perform 6 weeks of moderate intensity, whole-body elastic band training. Participants in the control group will participate in all testing procedures but not perform any training. Participants from both groups will be instructed to maintain their normal physical activity levels and dietary habits.

All training sessions will be home-based and virtually supervised by research personnel. Participants will complete 2 training sessions in the first week and 3 training sessions per week for the remaining 5 weeks. Each training session will last about 45-60 minutes and consist of 7 exercises performed in the same order by each participant, including both multi-joint (chair squat, chest press, leg press, back row) and single-joint (knee extension, knee flexion, elbow flexion) exercises. Participants will perform 12 repetitions for each exercise for the first 3 weeks, then volume will be increased by progressing to 4 sets for the remaining 3 weeks. There will be a 60-second rest interval between sets and a similar tempo will be used between groups.

Both training groups will perform the same training protocol, but participants in the maximal mental effort group will mentally urge their muscles to contract maximally during each repetition. That is, despite using a moderate intensity, participants will imagine the feeling of maximal muscle contraction of the primary muscles during each repetition.

Several measures of strength, neuromuscular function, physical function, and body composition will be measured before and after the training or control period.

Recruitment & Eligibility

Status
RECRUITING
Sex
Female
Target Recruitment
45
Inclusion Criteria
  • Between 65-79 years of age
  • Female
  • Have not engaged in structured exercise for 3 years
  • Are not reliant upon a walking aid
  • Be able to rise from a chair unassisted
  • BMI between 25-33 kg/m²
  • Have access to the internet and access to a smartphone or computer with a camera at home
Exclusion Criteria
  • Any history of cardiovascular, cerebrovascular, or metabolic diseases
  • Musculoskeletal injury within the past 6 months
  • Any condition affecting muscle function
  • Uncontrolled hypertension
  • Score less than 23 on the Mini-mental State Exam
  • Upon starting study, missing more than 2 training session

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Elastic Band TrainingElastic Band TrainingThis group will perform moderate intensity, whole-body elastic band training.
Elastic Band Training with Maximal Mental EffortElastic Band Training with Maximal Mental EffortThis group will perform moderate intensity, whole-body elastic band training with maximal mental effort during muscle contraction.
Primary Outcome Measures
NameTimeMethod
Change in bicep curl strength as measured by load lifted in poundsBaseline, Week 7

Maximum dumbbell load lifted successfully throughout the range of motion of a bicep curl

Secondary Outcome Measures
NameTimeMethod
Change in isometric bicep strength as measured by newton-meters of torqueBaseline, Week 7

Isometric strength of a muscle

Change in voluntary activation as measured by ratio of superimposed torque to resting twitch torqueBaseline, Week 7

Voluntary activation is an estimate of neural drive and is the amplitude of superimposed torque elicited by percutaneous muscle stimulation relative to the resting twitch torque amplitude

Change in handgrip strength as measured in kilograms of forceBaseline, Week 7

Upper-body strength as measured by a handgrip dynamometer

Change in antagonist co-activation as measured by electromyography amplitudeBaseline, Week 7

A measure of the capacity at which the antagonist muscle is activated by the nervous system

Change in isokinetic bicep strength as measured by newton-meters of torqueBaseline, Week 7

Dynamic strength of a muscle contracting at a constant velocity

Change in chair rise performance as measured by number of chair rises performed in 30 secondsBaseline, Week 7

Measure of lower-body physical function

Change in resting heart rate as measured by beats/min using oscillatory cuffBaseline, Week 7

Measure of cardiovascular fitness

Change in rate of torque development as measured by newton-meters per secondBaseline, Week 7

A measure of the capacity to increase muscle torque rapidly as determined by the slope of the torque-time curve

Change in agonist muscle activation as measured by electromyography amplitudeBaseline, Week 7

A measure of the capacity at which the muscle is activitated by the nervous system

Change in walking speed as measured by time taken to walk 6 metersBaseline, Week 7

Measure of lower-body physical function

Change from baseline in isokinetic muscle activation at 6 weeksBaseline, Week 7

Electromyography root mean square during isokinetic contraction divided by root mean square during isometric contraction

Change in muscle composition as measured by ultrasound-derived grey-scale analysisBaseline, Week 7

Echo-intensity value derived from grey-scale analysis is indicative of amount of non-contractile tissue in muscle

Change in fat-free mass as measured by kilogramsBaseline, Week 7

Amount of non-fat tissue a person possesses estimated by bioelectrical impedance analysis

Change in general feeling about knee extension and bicep curl exerciseEach exercise session of the 6-week intervention

From a -5 to +5 on the Affective Feeling Scale

Change in grip width on elastic band as measured by distance of hand placements on bandBaseline, 3 weeks, 5 weeks

Indication of progression in training intensity

Change in skeletal muscle size as measured by ultrasound-derived cross-sectionalBaseline, Week 7

Size of a muscle

Change in body fat percentage as measured by fat tissue relative to fat-free tissueBaseline, Week 7

Relative amount of body fat a person possesses estimated by bioelectrical impedance analysis

Change in chair rise power by watts by a linear transducer attached to hip during chair rise testBaseline, Week 7

Product of load and velocity as determined on a linear transducer

Change in fat mass as measured by kilogramsBaseline, Week 7

Amount of fat tissue a person possesses estimated by bioelectrical impedance analysis

Change in hemoglobin A1c level as measured by blood drop analysisBaseline, Week 7

Blood drop analysis, obtained from fingerstick, measure of amount of blood sugar bound to hemoglobin

Change in resting blood pressure in millimeters of mercury using oscillatory cuffBaseline, Week 7

Measure of cardiovascular fitness

Trial Locations

Locations (1)

Kennesaw State University

🇺🇸

Kennesaw, Georgia, United States

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